Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50009493
TargetMetabotropic glutamate receptor 1(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50079183(amino(3,5-dihydroxyphenyl)acetic acid | 3,5-DHPG |...)
Affinity DataEC50:  6.60E+3nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084139(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataEC50:  1.03E+5nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084142(CHPG | CHEMBL345498 | Amino-(2-chloro-5-hydroxy-ph...)
Affinity DataEC50:  7.50E+5nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...)
Affinity DataIC50: 36nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084141((E)-2-methyl-6-styrylpyridine | SIB-1757 | 2-Methy...)
Affinity DataIC50: 290nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataIC50: 370nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 8.80E+3nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084139(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM86717(CAS_5218788 | NSC_5218788 | CHEMBL88553 | SIB-1757)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084141((E)-2-methyl-6-styrylpyridine | SIB-1757 | 2-Methy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084140(LY-367385 | 4-((S)-Amino-carboxy-methyl)-3-methyl-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084136((R)-1-Amino-indan-1,5-dicarboxylic acid | CHEMBL35...)
Affinity DataIC50: 2.14E+5nMAssay Description:Compound was tested for its agonist activity against Ser165 and Thr188 (Metabotropic glutamate receptor 1) receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Universit¿A Di Perugia

Curated by ChEMBL
LigandPNGBDBM50084136((R)-1-Amino-indan-1,5-dicarboxylic acid | CHEMBL35...)
Affinity DataIC50: 1.00E+6nMAssay Description:Compound was tested for it's antagonist activity against Ser152 and Thr175 (Metabotropic glutamate receptor 5)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed