Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50035078
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataEC50:  0.00700nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50169743(CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...)
Affinity DataIC50: 0.470nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 0.720nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 3nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366659(CHEMBL1627354)
Affinity DataIC50: 3.5nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM17292([2,4,6,7-3H]-17beta-estradiol | [3H]-estradiol | 1...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366661(CHEMBL1627355)
Affinity DataEC50:  5nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50169743(CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366664(CHEMBL1627353)
Affinity DataEC50:  7nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50169743(CHEMBL1358 | (7R,8R,9S,13S,14S,17S)-13-methyl-7-(9...)
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366659(CHEMBL1627354)
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366659(CHEMBL1627354)
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366658(CHEMBL1628170)
Affinity DataEC50:  13nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366658(CHEMBL1628170)
Affinity DataIC50: 21nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366660(CHEMBL1628199)
Affinity DataEC50:  28nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366663(CHEMBL1627351)
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366663(CHEMBL1627351)
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366660(CHEMBL1628199)
Affinity DataIC50: 33nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366660(CHEMBL1628199)
Affinity DataIC50: 37nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50041611((E)-3-[4-((Z)-1,2-Diphenyl-but-1-enyl)-phenyl]-acr...)
Affinity DataIC50: 39nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366663(CHEMBL1627351)
Affinity DataEC50:  40nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366658(CHEMBL1628170)
Affinity DataIC50: 46nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50041611((E)-3-[4-((Z)-1,2-Diphenyl-but-1-enyl)-phenyl]-acr...)
Affinity DataIC50: 56nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366662(CHEMBL1627356)
Affinity DataIC50: 59nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366664(CHEMBL1627353)
Affinity DataIC50: 63nMAssay Description:Displacement of [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366662(CHEMBL1627356)
Affinity DataIC50: 94nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366662(CHEMBL1627356)
Affinity DataEC50:  173nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366663(CHEMBL1627351)
Affinity DataIC50: 316nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366657(CHEMBL1627361)
Affinity DataEC50:  336nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366664(CHEMBL1627353)
Affinity DataIC50: 397nMAssay Description:Agonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50366660(CHEMBL1628199)
Affinity DataIC50: 519nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50041611((E)-3-[4-((Z)-1,2-Diphenyl-but-1-enyl)-phenyl]-acr...)
Affinity DataIC50: 654nMAssay Description:Antagonist effect on transcriptional activation in MCF-7 cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)