Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50036910
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 36.4nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16496(CHEMBL10413 | FR 74366 | [3-(4-bromo-2-fluorobenzy...)
Affinity DataIC50: 42.4nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16314(N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]c...)
Affinity DataIC50: 47nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50010283(Imirestat | 2,7-difluorospiro[9H-fluorene-9,4'-(te...)
Affinity DataIC50: 54.7nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50009777(Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...)
Affinity DataIC50: 66.5nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50038843(2-(4-bromo-2-fluorobenzyl)-6-fluoro-1H,2'H,5'H-spi...)
Affinity DataIC50: 72.6nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50086037(6-fluoro-2-methyl-1H,2'H,5'H-spiro[isoquinoline-4,...)
Affinity DataIC50: 73.2nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50086038(6-chloro-2-methylspiro[1,2,3,4-tetrahydroisoquinol...)
Affinity DataIC50: 78.2nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50038846(6-fluoro-2-(5-trifluoromethylbenzo[d][1,3]thiazol-...)
Affinity DataIC50: 144nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM50086039([2-(4-Bromo-2-fluoro-benzyl)-6-fluoro-1,3-dioxo-1,...)
Affinity DataIC50: 227nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
National Eye Institute

Curated by ChEMBL
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 919nMAssay Description:Inhibitory Activity against Human recombinant Aldose Reductase (wild type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed