Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50042037
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50420186(ZOSUQUIDAR | ZOSUQUIDAR TRIHYDROCHLORIDE)
Affinity DataIC50: 20nMAssay Description:TP_TRANSPORTER: inhibition of Nelfinavir transepithelial transport (basal to apical) (Nelfinavir: 0.02 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50420186(ZOSUQUIDAR | ZOSUQUIDAR TRIHYDROCHLORIDE)
Affinity DataIC50: 24nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50420186(ZOSUQUIDAR | ZOSUQUIDAR TRIHYDROCHLORIDE)
Affinity DataIC50: 50nMAssay Description:TP_TRANSPORTER: inhibition of Indinavir transepithelial transport (basal to apical) (Indinavir: 0.05 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50420186(ZOSUQUIDAR | ZOSUQUIDAR TRIHYDROCHLORIDE)
Affinity DataIC50: 50nMAssay Description:TP_TRANSPORTER: inhibition of Indinavir transepithelial transport (basal to apical) (Indinavir: 0.05 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50390978(VALSPODAR)
Affinity DataIC50: 110nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 1.20E+3nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 1.30E+3nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50366785(NELFINAVIR)
Affinity DataIC50: 1.40E+3nMAssay Description:TP_TRANSPORTER: inhibition of Daunorubicin transepithelial transport (basal to apical) (Daunorubicin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50338982((R)-5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3...)
Affinity DataIC50: 2.10E+3nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50017681(Quinatime | Quinine | (6-Methoxy-quinolin-4-yl)-(5...)
Affinity DataIC50: 2.20E+3nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM520(ABT-538 | Norvir | CHEMBL163 | 1,3-thiazol-5-ylmet...)
Affinity DataIC50: 3.80E+3nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM519(SQV | Invirase | CHEMBL114 | Ro 31-8959 | Fortovas...)
Affinity DataIC50: 6.50E+3nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM517(Crixivan | CHEMBL115 | L-735, 524 | MK639 | Indina...)
Affinity DataIC50: 4.40E+4nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details
PubMed