Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50036809
TargetType-2 angiotensin II receptor(Rat)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50035451(4'-[3-Butyl-5-oxo-1-(2-trifluoromet hyl-phenyl)-15...)
Affinity DataIC50: 0.450nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 2 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50044518(5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl...)
Affinity DataKi:  0.850nMAssay Description:Binding affinity to Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50035431(5-Butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50044543(5-Butyl-2-(2-isopropyl-phenyl)-4-[2'-(2H-tetrazol-...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to Angiotensin II receptor, type 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50088244(7-[3-(2-Cyclopropylmethyl-3-methoxymethyl-4-thiazo...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity to leukotriene B4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50037605(2-[2-(Benzothiazole-2-carbonyl)-pyrrolidine-1-carb...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Prolyl endopeptidase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50088245(4-[6-Amino-2-(4-formyl-phenylethynyl)-purin-9-yl]-...)
Affinity DataKi:  6.30nMAssay Description:Binding affinity to Adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetProlyl endopeptidase(Pig)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50088247(Oxo-{1-[1-(4-phenyl-butyryl)-pyrrolidine-2-carbony...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Prolyl endopeptidase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50035451(4'-[3-Butyl-5-oxo-1-(2-trifluoromet hyl-phenyl)-15...)
Affinity DataKi:  17nMAssay Description:Binding affinity to Angiotensin II receptor, type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50034013(9-Bromo-4-ethyl-4-hydroxy-11-methyl-1,12-dihydro-4...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against DNA topoisomerase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50035441(4'-[3-Butyl-1-(3-nitro-phenyl)-5-oxo-1,5-dihydro-[...)
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 2 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50088242(4-(6-Amino-2-thiazol-2-ylethynyl-purin-9-yl)-2,3-d...)
Affinity DataKi:  41nMAssay Description:Binding affinity to Adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50034014(4-Ethyl-4-hydroxy-11-methyl-3,13-dioxo-3,4,12,13-t...)
Affinity DataIC50: 143nMAssay Description:Inhibitory activity against DNA topoisomerase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50088241(3-(3,4-Dichloro-phenyl)-5-hydroxy-4-(4-methoxy-ben...)
Affinity DataKi:  170nMAssay Description:Binding affinity to Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Rat)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50035441(4'-[3-Butyl-1-(3-nitro-phenyl)-5-oxo-1,5-dihydro-[...)
Affinity DataKi:  173nMAssay Description:Binding affinity to Angiotensin II receptor, type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1(Human)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50088246(7-[3-(4-Acetyl-3-hydroxymethyl-2-propyl-phenoxy)-p...)
Affinity DataKi:  320nMAssay Description:Binding affinity to leukotriene B4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetEndothelin-1 receptor(Human)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50088243(3-Benzo[1,3]dioxol-5-yl-4-benzyl-5-(3,4-dichloro-p...)
Affinity DataKi:  400nMAssay Description:Binding affinity to Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
Neogenesis

Curated by ChEMBL
LigandPNGBDBM50035431(5-Butyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2012
Entry Details Article
PubMed