Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50009956
TargetAldo-keto reductase family 1 member B1(Human)
Rational Drug Design Laboratories

Curated by ChEMBL
LigandPNGBDBM16512((2S,4S)-6-fluoro-2,5-dioxo-2,3-dihydrospiro[chrome...)
Affinity DataIC50: 9nMAssay Description:Tested for in vitro inhibition activity against human Aldose reductase (human AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Rational Drug Design Laboratories

Curated by ChEMBL
LigandPNGBDBM16512((2S,4S)-6-fluoro-2,5-dioxo-2,3-dihydrospiro[chrome...)
Affinity DataIC50: 35nMAssay Description:Tested for in vitro inhibition activity against rat Aldose reductase (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Rat)
Rational Drug Design Laboratories

Curated by ChEMBL
LigandPNGBDBM50089423(6-fluoro-2',5'-dioxo-(2R,4'S)-spiro[3,4-dihydro-2H...)
Affinity DataIC50: 570nMAssay Description:Tested for in vitro inhibition activity against rat Aldose reductase (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Rat)
Rational Drug Design Laboratories

Curated by ChEMBL
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 900nMAssay Description:Tested for in vitro inhibition activity against rat Aldose reductase (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Human)
Rational Drug Design Laboratories

Curated by ChEMBL
LigandPNGBDBM16512((2S,4S)-6-fluoro-2,5-dioxo-2,3-dihydrospiro[chrome...)
Affinity DataIC50: 1.20E+3nMAssay Description:Tested for in vitro inhibition activity against human aldehyde reductase (AHR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Rational Drug Design Laboratories

Curated by ChEMBL
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for in vitro inhibition activity against human Aldose reductase (human AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member A1(Human)
Rational Drug Design Laboratories

Curated by ChEMBL
LigandPNGBDBM16312(CHEMBL266497 | (4S)-6-fluoro-2,3-dihydrospiro[1-be...)
Affinity DataIC50: 5.40E+3nMAssay Description:Tested for in vitro inhibition activity against human aldehyde reductase (AHR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed