Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50010067
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM12594(CHEMBL48813 | 4-({4-[(6-chloro-1-benzothiophene-2-...)
Affinity DataKi:  1.30nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  12nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  21nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090605(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  59nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090600(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  97nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090595(N-[2-(2-Amino-pyridin-4-yl)-ethyl]-2-[4-(6-chloro-...)
Affinity DataKi:  140nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090597(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  140nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090604(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  160nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090596(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  170nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090613(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  250nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090615(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  270nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090594(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  340nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090609(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  430nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090611(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi:  620nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090603(N-[2-(2-Amino-thiazol-4-yl)-ethyl]-2-[4-(6-chloro-...)
Affinity DataKi:  620nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090601(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090614(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090606(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090602((R)-2-{2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090599((S)-2-{2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090598(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090608(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090612(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090607(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090610(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.20E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >2.90E+3nMAssay Description:Compound was evaluated for the inhibitory activity against trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >2.90E+3nMAssay Description:Compound was evaluated for the inhibitory activity against trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >4.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >4.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >7.30E+3nMAssay Description:Compound was evaluated for the inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >7.30E+3nMAssay Description:Compound was evaluated for the inhibitory activity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >8.70E+3nMAssay Description:Compound was evaluated for the inhibitory activity against t-PAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >8.70E+3nMAssay Description:Compound was evaluated for the inhibitory activity against t-PAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090592(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.80E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Activated protein CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50090593(2-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo...)
Affinity DataKi: >1.80E+4nMAssay Description:Compound was evaluated for the inhibitory activity against Activated protein CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed