Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50010081
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090771((R)-1-[3-(Isopropyl-propyl-amino)-chroman-5-yl]-et...)
Affinity DataKi:  0.300nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090762((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi:  0.320nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090763((S)-3-{[4-(7,9-Dioxo-8-aza-spiro[4.5]dec-8-yl)-but...)
Affinity DataKi:  0.340nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090756((R)-3-(Cyclopentyl-propyl-amino)-chroman-5-carboxy...)
Affinity DataKi:  0.410nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090764((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi:  0.480nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090772((R)-3-(Isobutyl-propyl-amino)-chroman-5-carboxylic...)
Affinity DataKi:  2.37nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090770((R)-Isopropyl-(5-methoxy-chroman-3-yl)-propyl-amin...)
Affinity DataKi:  3.10nMAssay Description:In vitro binding affinity at 5-HT1A receptor by measuring its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090771((R)-1-[3-(Isopropyl-propyl-amino)-chroman-5-yl]-et...)
Affinity DataKi:  11.9nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090759((R)-3-Dipropylamino-chroman-5-carboxylic acid isop...)
Affinity DataKi:  14nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090761((R)-3-(Cyclopentyl-propyl-amino)-chroman-5-carboxy...)
Affinity DataKi:  18.5nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090759((R)-3-Dipropylamino-chroman-5-carboxylic acid isop...)
Affinity DataKi:  64nMAssay Description:In vitro binding affinity at 5-HT1A receptor by measuring its ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocamp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090754((R)-3-Propylamino-chroman-5-carboxylic acid amide ...)
Affinity DataKi:  98.4nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090770((R)-Isopropyl-(5-methoxy-chroman-3-yl)-propyl-amin...)
Affinity DataKi:  134nMAssay Description:In vitro binding affinity at 5-HT1A receptor by measuring its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090757((R)-3-Isopropylamino-chroman-5-carboxylic acid ami...)
Affinity DataKi:  397nMAssay Description:In vitro binding affinity at 5-HT1A receptors assayed by displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampal membra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090754((R)-3-Propylamino-chroman-5-carboxylic acid amide ...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin from rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090764((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin from rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090759((R)-3-Dipropylamino-chroman-5-carboxylic acid isop...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin from rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090754((R)-3-Propylamino-chroman-5-carboxylic acid amide ...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2A measured by ability to displace [3H]raclopride from D2A receptor expressed in mouse f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090754((R)-3-Propylamino-chroman-5-carboxylic acid amide ...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at D1 receptor by measuring its ability to displace [3H]SCH-23390 from Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090759((R)-3-Dipropylamino-chroman-5-carboxylic acid isop...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2A measured by ability to displace [3H]raclopride from D2A receptor expressed in mouse f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090758((R)-3-(Cyclopentyl-propyl-amino)-chroman-5-carboxy...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin from rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090757((R)-3-Isopropylamino-chroman-5-carboxylic acid ami...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at D1 receptor by measuring its ability to displace [3H]SCH-23390 from Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090757((R)-3-Isopropylamino-chroman-5-carboxylic acid ami...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin from rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090757((R)-3-Isopropylamino-chroman-5-carboxylic acid ami...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2A measured by ability to displace [3H]raclopride from D2A receptor expressed in mouse f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090764((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at D1 receptor by measuring its ability to displace [3H]SCH-23390 from Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090758((R)-3-(Cyclopentyl-propyl-amino)-chroman-5-carboxy...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2A measured by ability to displace [3H]raclopride from D2A receptor expressed in mouse f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090759((R)-3-Dipropylamino-chroman-5-carboxylic acid isop...)
Affinity DataKi: >1.00E+3nMAssay Description:In vitro binding affinity at D1 receptor by measuring its ability to displace [3H]SCH-23390 from Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090758((R)-3-(Cyclopentyl-propyl-amino)-chroman-5-carboxy...)
Affinity DataKi: >4.00E+3nMAssay Description:In vitro binding affinity at D1 receptor by measuring its ability to displace [3H]SCH-23390 from Dopamine receptor D1 in rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090771((R)-1-[3-(Isopropyl-propyl-amino)-chroman-5-yl]-et...)
Affinity DataKi:  3.01E+4nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2A by measuring its ability to displace [3H]raclopride from D2A receptor expressed in mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090764((R)-3-(Isopropyl-propyl-amino)-chroman-5-carboxyli...)
Affinity DataKi: >5.00E+4nMAssay Description:In vitro binding affinity at human cloned Dopamine receptor D2A measured by ability to displace [3H]raclopride from D2A receptor expressed in mouse f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Astrazeneca R&D SöDertäLje

Curated by ChEMBL
LigandPNGBDBM50090772((R)-3-(Isobutyl-propyl-amino)-chroman-5-carboxylic...)
Affinity DataKi: >5.00E+4nMAssay Description:In vitro binding affinity at 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin from rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed