Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50036843
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50091405(1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R)-12...)
Affinity DataKi:  0.460nMAssay Description:Displacement of radioligand [3H]- U-69,593 on Opioid receptor kappa 1 in monkey brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50091405(1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R)-12...)
Affinity DataKi:  0.460nMAssay Description:Displacement of radioligand [3H]- DAMGO on Opioid receptor mu 1 in monkey brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50091404(1N-[4-cyclopropylmethyl-14-oxo-(13R)-12-oxa-4-azap...)
Affinity DataKi:  0.540nMAssay Description:Displacement of radioligand [3H]- DAMGO on Opioid receptor mu 1 in monkey brain membranes range; Value ranges from (0.32-0.91)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50066535(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(17S)-12...)
Affinity DataKi:  1.60nMAssay Description:Displacement of radioligand [3H]- DPDPE on Opioid receptor delta 1 in monkey brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50066535(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(17S)-12...)
Affinity DataKi:  1.60nMAssay Description:Displacement of radioligand [3H]- DAMGO on Opioid receptor mu 1 in monkey brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50066535(1N-[4-cyclopropylmethyl-10-hydroxy-14-oxo-(17S)-12...)
Affinity DataKi:  1.60nMAssay Description:Displacement of radioligand [3H]- U-69,593 on Opioid receptor kappa 1 in monkey brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50091405(1N-[4-cyclopropylmethyl-10-methoxy-14-oxo-(13R)-12...)
Affinity DataKi:  4.5nMAssay Description:Displacement of radioligand [3H]- DPDPE on Opioid receptor delta 1 in monkey brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50091404(1N-[4-cyclopropylmethyl-14-oxo-(13R)-12-oxa-4-azap...)
Affinity DataKi:  12nMAssay Description:Displacement of radioligand [3H]- U-69,593 on Opioid receptor kappa 1 in monkey brain membranes range; Value ranges from (9.7-14.2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50091404(1N-[4-cyclopropylmethyl-14-oxo-(13R)-12-oxa-4-azap...)
Affinity DataKi:  37nMAssay Description:Displacement of radioligand [3H]- DPDPE on Opioid receptor delta 1 in monkey brain membranes range; Value ranges from (34.0-43.2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed