Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50010133
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774(CHEMBL311347 | (2S,3S)-methyl 3-(4-iodophenyl)-8-m...)
Affinity DataKi:  0.460nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091436(8-Methyl-3-(3'-nitro-biphenyl-4-yl)-8-aza-bicyclo[...)
Affinity DataKi:  0.800nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774(CHEMBL311347 | (2S,3S)-methyl 3-(4-iodophenyl)-8-m...)
Affinity DataKi:  0.960nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091437(3-(3'-Hydroxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  1.40nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091434(3-(3'-Methoxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  1.90nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50006774(CHEMBL311347 | (2S,3S)-methyl 3-(4-iodophenyl)-8-m...)
Affinity DataKi:  2.80nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091435(8-Methyl-3-(4'-nitro-biphenyl-4-yl)-8-aza-bicyclo[...)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091436(8-Methyl-3-(3'-nitro-biphenyl-4-yl)-8-aza-bicyclo[...)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091428(3-(3'-Acetyl-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091432(3-(4'-Methoxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091437(3-(3'-Hydroxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091433(3-(4'-Acetyl-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091427(3-(3'-Amino-biphenyl-4-yl)-8-methyl-8-aza-bicyclo[...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091435(8-Methyl-3-(4'-nitro-biphenyl-4-yl)-8-aza-bicyclo[...)
Affinity DataKi:  30nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091432(3-(4'-Methoxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  32nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091428(3-(3'-Acetyl-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  42nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091434(3-(3'-Methoxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091427(3-(3'-Amino-biphenyl-4-yl)-8-methyl-8-aza-bicyclo[...)
Affinity DataKi:  67nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091430(3-(2'-Methoxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  80nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091433(3-(4'-Acetyl-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  179nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091432(3-(4'-Methoxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  352nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091430(3-(2'-Methoxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  357nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091435(8-Methyl-3-(4'-nitro-biphenyl-4-yl)-8-aza-bicyclo[...)
Affinity DataKi:  370nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091433(3-(4'-Acetyl-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  754nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091436(8-Methyl-3-(3'-nitro-biphenyl-4-yl)-8-aza-bicyclo[...)
Affinity DataKi:  963nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091429(3-(2'-Acetyl-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091431(8-Methyl-3-(2'-nitro-biphenyl-4-yl)-8-aza-bicyclo[...)
Affinity DataKi: >3.00E+3nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091431(8-Methyl-3-(2'-nitro-biphenyl-4-yl)-8-aza-bicyclo[...)
Affinity DataKi: >3.00E+3nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091434(3-(3'-Methoxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi: >3.00E+3nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091431(8-Methyl-3-(2'-nitro-biphenyl-4-yl)-8-aza-bicyclo[...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]GBR-12935 from rat forebrain Dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091429(3-(2'-Acetyl-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi:  5.00E+3nMAssay Description:Affinity for Serotonin transporter by displacing [3H]paroxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091430(3-(2'-Methoxy-biphenyl-4-yl)-8-methyl-8-aza-bicycl...)
Affinity DataKi:  1.00E+4nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091429(3-(2'-Acetyl-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi: >2.00E+4nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Yale University

Curated by ChEMBL
LigandPNGBDBM50091428(3-(3'-Acetyl-biphenyl-4-yl)-8-methyl-8-aza-bicyclo...)
Affinity DataKi: >5.00E+4nMAssay Description:Compound has been evaluated for its affinity towards Norepinephrine transporter by displacing the radio isotope [3H]nisoxetine from rat forebrainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed