Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50010136
TargetC-C chemokine receptor type 5(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 1.40nMAssay Description:Compound was evaluated for the antagonist activity against C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 27nMAssay Description:Compound was evaluated for the antagonist activity against C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091440(1'-{2-[2-(4-fluorophenyl)-5-methyl-1,3-oxazol-4-yl...)
Affinity DataIC50: 32nMAssay Description:Compound was evaluated for the antagonist activity against C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091438((E)-3-(3,4-dichlorophenyl)-N-(5-(4-(5-hydroxy-1H-i...)
Affinity DataKi:  50nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091449(TCMDC-139325 | (E)-3-(3,4-Dichloro-phenyl)-N-{5-[4...)
Affinity DataKi:  79nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091457((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-2-m...)
Affinity DataKi:  234nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091454((E)-3-(4-Bromo-phenyl)-N-{5-[4-(1H-indol-3-yl)-pip...)
Affinity DataKi:  350nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091451((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(6-hydroxy-1H-...)
Affinity DataKi:  360nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091461((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(4-hydroxy-1H-...)
Affinity DataKi:  360nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091458((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...)
Affinity DataKi:  420nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091465((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...)
Affinity DataKi:  460nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091445((E)-3-(4-Chloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...)
Affinity DataKi:  520nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091471(TCMDC-139236 | (E)-N-{5-[4-(1H-Indol-3-yl)-piperid...)
Affinity DataKi:  550nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091460((E)-3-(3-Chloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...)
Affinity DataKi:  560nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091470((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-methoxy-1H-...)
Affinity DataKi:  590nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091442(TCMDC-139333 | (E)-3-(3,4-Dichloro-phenyl)-N-{4-[4...)
Affinity DataKi:  660nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091467((E)-N-{5-[4-(1H-Indol-3-yl)-piperidin-1-yl]-pentyl...)
Affinity DataKi:  790nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091448((E)-N-{5-[4-(1H-Indol-3-yl)-piperidin-1-yl]-pentyl...)
Affinity DataKi:  790nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091439((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)c...)
Affinity DataKi:  870nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091468((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...)
Affinity DataKi:  1.20E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091443((E)-3-Biphenyl-4-yl-N-{5-[4-(1H-indol-3-yl)-piperi...)
Affinity DataKi:  1.45E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091441(1-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-3-(3...)
Affinity DataKi:  1.60E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091447((E)-3-(4-tert-Butyl-phenyl)-N-{5-[4-(1H-indol-3-yl...)
Affinity DataKi:  1.70E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091453((E)-N-(3-(4-(1H-indol-3-yl)piperidin-1-yl)propyl)-...)
Affinity DataKi:  2.50E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091446((E)-3-(4-Cyano-phenyl)-N-{5-[4-(1H-indol-3-yl)-pip...)
Affinity DataKi:  2.80E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091452((E)-3-(4-Acetylamino-phenyl)-N-{5-[4-(1H-indol-3-y...)
Affinity DataKi:  2.90E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091456(TCMDC-139364 | (E)-3-(3,4-Dichloro-phenyl)-N-{5-[4...)
Affinity DataKi:  4.20E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091438((E)-3-(3,4-dichlorophenyl)-N-(5-(4-(5-hydroxy-1H-i...)
Affinity DataKi:  4.26E+3nMAssay Description:Compound was evaluated for the antagonist activity against C-C chemokine receptor type 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091466((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...)
Affinity DataKi:  4.40E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091464(2-(3,4-Dichloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...)
Affinity DataKi:  4.40E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091459(TCMDC-139112 | N-(5-(4-(1H-indol-3-yl)piperidin-1-...)
Affinity DataKi:  5.10E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091444(Biphenyl-4-carboxylic acid {5-[4-(1H-indol-3-yl)-p...)
Affinity DataKi:  5.30E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091444(Biphenyl-4-carboxylic acid {5-[4-(1H-indol-3-yl)-p...)
Affinity DataKi:  5.40E+3nMAssay Description:Antagonist activity against C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091450(3-(3,4-Dichloro-phenyl)-N-{5-[4-(1H-indol-3-yl)-pi...)
Affinity DataKi:  5.90E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091455((E)-N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-...)
Affinity DataKi:  6.30E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091472(N-(5-(4-(1H-indol-3-yl)piperidin-1-yl)pentyl)-4-br...)
Affinity DataKi:  7.10E+3nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091462((E)-3-(3,4-Dichloro-phenyl)-N-{2-[4-(1H-indol-3-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091469(Biphenyl-4-carboxylic acid {6-[4-(1H-indol-3-yl)-p...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091463(3,4-Dichloro-N-{5-[4-(1H-indol-3-yl)-piperidin-1-y...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was evaluated for the antagonist activity against human C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed