Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50035066
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091497((S)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18128(CHEMBL310012 | (2S)-2-[(2S)-2-amino-3-(4-hydroxyph...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50091496((R)-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataIC50: 21nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from Staphylococcus aureus was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetTyrosine--tRNA ligase, cytoplasmic(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18128(CHEMBL310012 | (2S)-2-[(2S)-2-amino-3-(4-hydroxyph...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory activity of compound against tyrosyl tRNA synthetase from mammalian cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed