Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50010346
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093750((6R,7R)-3-(1-Carboxymethyl-1H-tetrazol-5-ylsulfany...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093751((6R,7R)-7-Methoxy-7-(2-methoxy-benzoylamino)-3-(1-...)
Affinity DataIC50: 19nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093749((6R,7R)-7-Methoxy-3-(1-methyl-1H-tetrazol-5-ylsulf...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093747((6R,7R)-7-(2-sec-Butoxy-benzoylamino)-7-methoxy-3-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093745((6R,7R)-7-(2-Ethoxy-benzoylamino)-7-methoxy-3-(1-m...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093746((6R,7R)-7-(2-Isopropoxy-benzoylamino)-7-methoxy-3-...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093734((6R,7R)-7-[2-(4-Hydroxy-phenyl)-acetylamino]-7-met...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093748((6R,7R)-7-Methoxy-3-(1-methyl-1H-tetrazol-5-ylsulf...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093716((6R,7R)-3-(1-Carboxymethyl-1H-tetrazol-5-ylsulfany...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093735((6R,7R)-7-[2-(4-Hydroxy-phenyl)-acetylamino]-7-met...)
Affinity DataIC50: 77nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093745((6R,7R)-7-(2-Ethoxy-benzoylamino)-7-methoxy-3-(1-m...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration was measured against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093720((6R,7R)-7-[2-(4-Hydroxy-phenyl)-acetylamino]-7-met...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin G(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093745((6R,7R)-7-(2-Ethoxy-benzoylamino)-7-methoxy-3-(1-m...)
Affinity DataIC50: 280nMAssay Description:Inhibitory concentration was measured against cathepsin GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093730((6R,7R)-7-[2-(4-Dimethylamino-phenyl)-acetylamino]...)
Affinity DataIC50: 410nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093727((6R,7R)-7-Methoxy-7-(2-methoxy-benzoylamino)-3-(1-...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093745((6R,7R)-7-(2-Ethoxy-benzoylamino)-7-methoxy-3-(1-m...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibitory concentration was measured against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093745((6R,7R)-7-(2-Ethoxy-benzoylamino)-7-methoxy-3-(1-m...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibitory concentration was measured against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093745((6R,7R)-7-(2-Ethoxy-benzoylamino)-7-methoxy-3-(1-m...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibitory concentration was measured against elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymase(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093732((6R,7R)-7-[2-(4-Hydroxy-phenyl)-acetylamino]-7-met...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Serine protease chymaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Rat)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50093745((6R,7R)-7-(2-Ethoxy-benzoylamino)-7-methoxy-3-(1-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration was measured against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed