Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50010453
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 530nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094985(3-(4-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 4.80E+3nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094985(3-(4-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-...)
Affinity DataIC50: 6.50E+3nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094987(5-Hydroxy Rofecoxib | 5-Hydroxy-4-(4-methanesulfon...)
Affinity DataIC50: 8.70E+3nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 1.88E+4nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094983((3S,4S)-4-(4-Methanesulfonyl-phenyl)-3-phenyl-dihy...)
Affinity DataIC50: 3.00E+4nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094986(Sodium; (4R,5S)-6-hydroxy-5-(4-methanesulfonyl-phe...)
Affinity DataIC50: 3.30E+4nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094989((2S,3S)-4-Hydroxy-3-(4-methanesulfonyl-phenyl)-2-p...)
Affinity DataIC50: 3.30E+4nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50451154(CHEMBL2303697)
Affinity DataIC50: 3.30E+4nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50451153(Glucuronide Conjugate Of 5-Hydroxy Rofecoxib | CHE...)
Affinity DataIC50: 3.30E+4nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094988((3R,4S)-4-(4-Methanesulfonyl-phenyl)-3-phenyl-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094987(5-Hydroxy Rofecoxib | 5-Hydroxy-4-(4-methanesulfon...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094989((2S,3S)-4-Hydroxy-3-(4-methanesulfonyl-phenyl)-2-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094983((3S,4S)-4-(4-Methanesulfonyl-phenyl)-3-phenyl-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094986(Sodium; (4R,5S)-6-hydroxy-5-(4-methanesulfonyl-phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50094988((3R,4S)-4-(4-Methanesulfonyl-phenyl)-3-phenyl-dihy...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50451153(Glucuronide Conjugate Of 5-Hydroxy Rofecoxib | CHE...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50451154(CHEMBL2303697)
Affinity DataIC50: 1.00E+5nMAssay Description:The compound was evaluated for its inhibitory activity against COX- 1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed