Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50010480
LigandPNGBDBM50095232(6-Methoxy-7-(3-morpholin-4-yl-propoxy)-4-(4-phenox...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095232(6-Methoxy-7-(3-morpholin-4-yl-propoxy)-4-(4-phenox...)
Affinity DataIC50: 7nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095235(6-Methoxy-7-(2-morpholin-4-yl-ethoxy)-4-(4-phenoxy...)
Affinity DataIC50: 8nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095226(6,7-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095236(6-Methoxy-4-(4-phenoxy-phenylamino)-quinoline-3-ca...)
Affinity DataIC50: 18nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095235(6-Methoxy-7-(2-morpholin-4-yl-ethoxy)-4-(4-phenoxy...)
Affinity DataIC50: 25nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095229(7-(3-Morpholin-4-yl-propoxy)-4-(4-phenoxy-phenylam...)
Affinity DataIC50: 28nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095226(6,7-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095236(6-Methoxy-4-(4-phenoxy-phenylamino)-quinoline-3-ca...)
Affinity DataIC50: 35nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095230(5,7-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095229(7-(3-Morpholin-4-yl-propoxy)-4-(4-phenoxy-phenylam...)
Affinity DataIC50: 68nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095234(7-Methoxy-4-(4-phenoxy-phenylamino)-quinoline-3-ca...)
Affinity DataIC50: 90nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095239(6,7-Dimethoxy-4-(3-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 95nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095231(5-Methoxy-4-(4-phenoxy-phenylamino)-quinoline-3-ca...)
Affinity DataIC50: 98nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095239(6,7-Dimethoxy-4-(3-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095233(4-(4-Phenoxy-phenylamino)-quinoline-3-carbonitrile...)
Affinity DataIC50: 125nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095234(7-Methoxy-4-(4-phenoxy-phenylamino)-quinoline-3-ca...)
Affinity DataIC50: 125nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095230(5,7-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 185nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095231(5-Methoxy-4-(4-phenoxy-phenylamino)-quinoline-3-ca...)
Affinity DataIC50: 450nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095233(4-(4-Phenoxy-phenylamino)-quinoline-3-carbonitrile...)
Affinity DataIC50: 680nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095228(8-Methoxy-4-(4-phenoxy-phenylamino)-quinoline-3-ca...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095237(5,8-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095240(6,7,8-Trimethoxy-4-(4-phenoxy-phenylamino)-quinoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095237(5,8-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095238(6,7-Dimethoxy-4-(2-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095238(6,7-Dimethoxy-4-(2-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095240(6,7,8-Trimethoxy-4-(4-phenoxy-phenylamino)-quinoli...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095228(8-Methoxy-4-(4-phenoxy-phenylamino)-quinoline-3-ca...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50095227((6,7-Dimethoxy-quinazolin-4-yl)-(4-phenoxy-phenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ERK phosphorylation in coupled Raf-MEK-ERK ELISA (Weakly active)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed