Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50010528
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50008321(CHEMBL275599 | 6-(3,5-Dimethyl-phenylsulfanyl)-1-(...)
Affinity DataEC50:  260nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004126(CHEMBL39093 | 5-Cyclopropyl-1-ethoxymethyl-6-pheny...)
Affinity DataEC50:  100nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004132(CHEMBL288728 | 1-Butyl-5-methyl-6-phenylsulfanyl-1...)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004140(CHEMBL290413 | 5-Methyl-6-phenylsulfanyl-1H-pyrimi...)
Affinity DataEC50: >2.50E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004142(CHEMBL290685 | 1,5-Dimethyl-6-phenylsulfanyl-1H-py...)
Affinity DataEC50: >1.50E+5nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50008329(CHEMBL276108 | 6-(3,5-Dimethyl-phenylsulfanyl)-1-(...)
Affinity DataEC50:  2.70nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004152(CHEMBL31871 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl-...)
Affinity DataEC50:  7.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004146(CHEMBL40091 | 5-Methyl-6-phenylsulfanyl-1-propoxym...)
Affinity DataEC50:  3.60E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50010990(CHEMBL36427 | 6-Benzyl-1-(2-hydroxy-ethoxymethyl)-...)
Affinity DataEC50:  2.30E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50010998(CHEMBL286769 | 1-(2-Hydroxy-ethoxymethyl)-5-methyl...)
Affinity DataEC50:  8.50E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004124(CHEMBL288688 | 1-Benzyloxymethyl-5-ethyl-6-phenyls...)
Affinity DataEC50:  5.90nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM10904(1-[(benzyloxy)methyl]-6-(phenylthio)-thymine | CHE...)
Affinity DataEC50:  88nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004129(CHEMBL36995 | 1-Ethoxymethyl-5-ethyl-6-phenylsulfa...)
Affinity DataEC50:  19nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM2337(CHEMBL35033 | 6-benzyl-1-(ethoxymethyl)-5-(propan-...)
Affinity DataEC50:  4nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004136(CHEMBL38768 | 1-Ethyl-5-methyl-6-phenylsulfanyl-1H...)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004119(CHEMBL38711 | 1-Ethoxymethyl-5-isopropyl-6-phenyls...)
Affinity DataEC50:  12nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004134(CHEMBL39047 | 1-Methoxymethyl-5-methyl-6-phenylsul...)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004151(CHEMBL37743 | 1-Ethoxymethyl-5-methyl-6-phenylsulf...)
Affinity DataEC50:  330nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50008310(CHEMBL16684 | 6-(3,5-Dimethyl-phenylsulfanyl)-5-et...)
Affinity DataEC50:  13nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50004148(CHEMBL39015 | 1-Benzyloxymethyl-5-isopropyl-6-phen...)
Affinity DataEC50:  2.70nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1517(CHEMBL37628 | 2-ethyl-7-methyl-2,4,9,15-tetraazatr...)
Affinity DataIC50: 35nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 84nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1666(7-chloro-2-ethyl-2,4,9,15-tetraazatricyclo[9.4.0.0...)
Affinity DataIC50: 95nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50095772(5,9-Diethyl-10-methyl-5,10-dihydro-4,5,6,10-tetraa...)
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1518(CHEMBL37343 | 2-ethyl-9-methyl-2,4,9,15-tetraazatr...)
Affinity DataIC50: 125nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1529(CHEMBL288336 | 5-chloro-2-ethyl-9-methyl-2,4,9,15-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1521(2-ethyl-5,9-dimethyl-2,4,9,15-tetraazatricyclo[9.4...)
Affinity DataIC50: 170nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1651(CHEMBL291024 | 2-ethyl-2,4,9,15-tetraazatricyclo[9...)
Affinity DataIC50: 440nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1652(2-cyclopropyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3...)
Affinity DataIC50: 450nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1656(9-methyl-2-propyl-2,4,9,15-tetraazatricyclo[9.4.0....)
Affinity DataIC50: 450nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1663(CHEMBL39950 | 2-ethyl-6,9-dimethyl-2,4,9,15-tetraa...)
Affinity DataIC50: 760nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1660(9-methyl-2-[(methylsulfanyl)methyl]-2,4,9,15-tetra...)
Affinity DataIC50: 850nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50095776(8-Chloro-5-ethyl-10-methyl-5,10-dihydro-4,5,6,10-t...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50095774(5-Cyclopropyl-9,10-dimethyl-5,10-dihydro-4,5,6,10-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50095775(5-Cyclopropyl-11-oxo-10,11-dihydro-5H-4,5,6,10-tet...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50095777(5-Ethyl-9,10-dimethyl-5,10-dihydro-4,5,6,10-tetraa...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50095773(5-(2-Fluoro-ethyl)-10-methyl-5,10-dihydro-4,5,6,10...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM1577(CHEMBL39343 | 2-cyclopropyl-7-(hydroxymethyl)-2,4,...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50095771(5-tert-Butyl-10-methyl-5,10-dihydro-4,5,6,10-tetra...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Yale University

Curated by ChEMBL
LigandPNGBDBM50095770(5-Acetyl-10-methyl-5,10-dihydro-4,5,6,10-tetraaza-...)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase at 37 degree CentigradeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed