Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50010529
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50006710(8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-di...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against cyclic AMP production in rat Adenosine A2A receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095786(1-(6-Amino-8-furan-2-yl-9-methyl-9H-purin-2-ylethy...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50: 17.2nMAssay Description:Inhibitory activity against cyclic AMP production in rat Adenosine A1 receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095793(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataIC50: 23nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095781(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataIC50: 49nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Eisai

Curated by ChEMBL
LigandPNGBDBM50006710(8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-di...)
Affinity DataIC50: 62nMAssay Description:Inhibitory activity against cyclic AMP production in rat Adenosine A1 receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095790(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataIC50: 63nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095787(3-[6-Amino-2-(1-hydroxy-cyclohexylethynyl)-9-methy...)
Affinity DataIC50: 72nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095788(1-[6-Amino-8-(2-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataIC50: 77nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095784(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095778(4-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataIC50: 150nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095782(1-[6-Amino-8-(4-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM82015(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM82015(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)
Affinity DataIC50: 415nMAssay Description:Inhibitory activity against cyclic AMP production in human Adenosine A2B receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM82015(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)
Affinity DataIC50: 454nMAssay Description:Inhibitory activity against cyclic AMP production in rat Adenosine A2A receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095779(1-[6-Amino-8-(4-chloro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50: 980nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM82015(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory activity against cyclic AMP production in human adenosine A3 receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM82015(1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione...)
Affinity DataIC50: 1.34E+3nMAssay Description:Binding Affinity for Adenosine A1 receptor expressed in CHO-K1 cells compared to [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50006710(8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-di...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50059376(L-249313 | 9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]tr...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50059376(L-249313 | 9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]tr...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibitory activity against cyclic AMP production in human Adenosine A1 receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095785(1-[6-Amino-9-methyl-8-(3-trifluoromethyl-phenyl)-9...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibitory activity on NECA-induced cyclic-AMP accumulation in CHO-K1 cells expressing human Adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50059376(L-249313 | 9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against cyclic AMP production in human Adenosine A2B receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibitory activity against cyclic AMP production in rat Adenosine A2A receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50059376(L-249313 | 9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]tr...)
Affinity DataIC50: 2.75E+4nMAssay Description:Inhibitory activity against cyclic AMP production in rat Adenosine A2A receptor assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095778(4-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  9.10nMAssay Description:Binding Affinity towards Adenosine A2A receptor expressed in HEK293 cells versus [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095790(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  9.80nMAssay Description:Binding Affinity towards Adenosine A2A receptor expressed in HEK293 cells versus [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095786(1-(6-Amino-8-furan-2-yl-9-methyl-9H-purin-2-ylethy...)
Affinity DataKi:  11nMAssay Description:Binding Affinity towards Adenosine A2A receptor expressed in HEK293 cells versus [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50059376(L-249313 | 9-Methyl-2-phenyl-5,9-dihydro-[1,2,4]tr...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards adenosine A3 receptor expressed in HEK293 cells versus [125I]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095787(3-[6-Amino-2-(1-hydroxy-cyclohexylethynyl)-9-methy...)
Affinity DataKi:  13nMAssay Description:Binding Affinity towards Adenosine A2A receptor expressed in HEK293 cells versus [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095784(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  13nMAssay Description:Binding Affinity towards Adenosine A2A receptor expressed in HEK293 cells versus [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095793(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  14nMAssay Description:Binding Affinity towards Adenosine A1 receptor expressed in CHO-K1 cells versus [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095788(1-[6-Amino-8-(2-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  15nMAssay Description:Binding Affinity towards Adenosine A2A receptor expressed in HEK293 cells versus [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095793(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  16nMAssay Description:Binding Affinity towards Adenosine A2A receptor expressed in HEK293 cells versus [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataKi:  18nMAssay Description:Binding Affinity towards Adenosine A1 receptor expressed in CHO-K1 cells versus [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095781(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  19nMAssay Description:Binding Affinity towards Adenosine A2A receptor expressed in HEK293 cells versus [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095788(1-[6-Amino-8-(2-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  19nMAssay Description:Binding Affinity towards Adenosine A1 receptor expressed in CHO-K1 cells versus [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095790(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  20nMAssay Description:Binding Affinity towards Adenosine A1 receptor expressed in CHO-K1 cells versus [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095786(1-(6-Amino-8-furan-2-yl-9-methyl-9H-purin-2-ylethy...)
Affinity DataKi:  25nMAssay Description:Binding Affinity towards Adenosine A1 receptor expressed in CHO-K1 cells versus [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095781(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  27nMAssay Description:Binding Affinity towards Adenosine A1 receptor expressed in CHO-K1 cells versus [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095784(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  29nMAssay Description:Binding Affinity towards Adenosine A1 receptor expressed in CHO-K1 cells versus [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095778(4-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  30nMAssay Description:Binding Affinity towards Adenosine A1 receptor expressed in CHO-K1 cells versus [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50006710(8-[2-(3,4-Dimethoxy-phenyl)-vinyl]-7-methyl-1,3-di...)
Affinity DataKi:  71nMAssay Description:Binding Affinity for adenosine A2A receptor expressed in HEK293 cells compared to [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095787(3-[6-Amino-2-(1-hydroxy-cyclohexylethynyl)-9-methy...)
Affinity DataKi:  130nMAssay Description:Binding Affinity towards Adenosine A1 receptor expressed in CHO-K1 cells versus [3H]CCPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095784(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  330nMAssay Description:Binding affinity towards adenosine A3 receptor expressed in HEK293 cells versus [125I]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095793(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  540nMAssay Description:Binding affinity towards adenosine A3 receptor expressed in HEK293 cells versus [125I]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095790(1-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity towards adenosine A3 receptor expressed in HEK293 cells versus [125I]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50079652((E)-1-[(R)-2-(2-Hydroxy-ethyl)-piperidin-1-yl]-3-(...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding Affinity for adenosine A2A receptor expressed in HEK293 cells compared to [3H]CGS-21680More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50095778(4-[6-Amino-8-(3-fluoro-phenyl)-9-methyl-9H-purin-2...)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity towards adenosine A3 receptor expressed in HEK293 cells versus [125I]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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