Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50010620
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096823((S)-6-Amino-2-[(S)-2-[(1-benzoyl-piperidine-4-carb...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096830((S)-6-Amino-2-[(S)-2-({1-[2-(3,5-difluoro-phenyl)-...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096824((S)-6-Amino-2-[(S)-2-[(1-benzyl-piperidine-4-carbo...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096829((S)-6-Amino-2-[(S)-2-{[1-(2-hydroxy-2,2-diphenyl-a...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096835((S)-6-Amino-2-[(S)-2-{[1-(3,4-difluoro-benzyl)-pip...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096822((S)-6-Amino-2-[(S)-2-[(1-benzyl-piperidine-3-carbo...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096810((S)-6-Amino-2-[(S)-2-[(1-diphenylacetyl-piperidine...)
Affinity DataKi:  5nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096812((S)-6-Amino-2-[(S)-2-{[1-(3-fluoro-benzyl)-piperid...)
Affinity DataKi:  5nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096816((S)-6-Amino-2-[(S)-2-{[1-(2,3-difluoro-benzyl)-pip...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096821((S)-6-Amino-2-[(S)-2-[(1-cyclohexylcarbamoyl-piper...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096820((S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-((S)-1-...)
Affinity DataKi:  8.60nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096831((S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(3-meth...)
Affinity DataKi:  9nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096811((S)-6-Amino-2-[(S)-2-[(1-benzoyl-piperidine-3-carb...)
Affinity DataKi:  10nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096827((S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(3-meth...)
Affinity DataKi:  10nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096832((S)-6-Amino-2-[(S)-2-{[1-(2-benzo[1,3]dioxol-5-yl-...)
Affinity DataKi:  10nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096819(3-{3-[(S)-1-((S)-5-Amino-1-tert-butoxycarbonyl-pen...)
Affinity DataKi:  11nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096804((S)-6-Amino-2-{(S)-3-(1H-indol-3-yl)-2-[(1-phenylc...)
Affinity DataKi:  11nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096833((S)-6-Amino-2-[(S)-2-{[1-(4-fluoro-benzenesulfonyl...)
Affinity DataKi:  11nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096834((S)-6-Amino-2-[(S)-2-{[1-(4-chloro-benzo[1,3]dioxo...)
Affinity DataKi:  12nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096836((S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(thioph...)
Affinity DataKi:  14nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096825((S)-6-Amino-2-{(S)-3-(1H-indol-3-yl)-2-[(1-isobuty...)
Affinity DataKi:  15nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096809((S)-6-Amino-2-{(S)-3-(1H-indol-3-yl)-2-[(1-naphtha...)
Affinity DataKi:  17nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096815((S)-6-Amino-2-[(S)-2-[(1-biphenyl-2-ylmethyl-piper...)
Affinity DataKi:  21nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096813((S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(3-meth...)
Affinity DataKi:  23nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096808((S)-6-Amino-2-[(S)-2-{[1-(3,4-dimethoxy-benzenesul...)
Affinity DataKi:  23nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096805((S)-6-Amino-2-[(S)-2-[(1-benzhydryl-piperidine-3-c...)
Affinity DataKi:  31nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096828((S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(propan...)
Affinity DataKi:  35nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096814((S)-6-Amino-2-[(S)-2-{[1-(benzo[1,3]dioxole-5-carb...)
Affinity DataKi:  36nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096826((S)-2-[(S)-2-{[1-(3-Acetylamino-benzoyl)-piperidin...)
Affinity DataKi:  47nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096837((S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(pyridi...)
Affinity DataKi:  85nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096807((S)-6-Amino-2-[(S)-2-{[1-(1H-benzoimidazole-5-carb...)
Affinity DataKi:  85nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096806((S)-6-Amino-2-{(S)-3-(1H-indol-3-yl)-2-[(1-isoprop...)
Affinity DataKi:  95nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096817((S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(propan...)
Affinity DataKi:  120nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096818((S)-6-Amino-2-{(S)-3-(1H-indol-3-yl)-2-[(piperidin...)
Affinity DataKi:  178nMAssay Description:Binding affinity to Somatostatin receptor type 2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096824((S)-6-Amino-2-[(S)-2-[(1-benzyl-piperidine-4-carbo...)
Affinity DataKi:  333nMAssay Description:Binding affinity to hsst5 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096823((S)-6-Amino-2-[(S)-2-[(1-benzoyl-piperidine-4-carb...)
Affinity DataKi:  416nMAssay Description:Binding affinity to hsst5 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096823((S)-6-Amino-2-[(S)-2-[(1-benzoyl-piperidine-4-carb...)
Affinity DataKi:  2.66E+3nMAssay Description:Binding affinity to hsst3 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096825((S)-6-Amino-2-{(S)-3-(1H-indol-3-yl)-2-[(1-isobuty...)
Affinity DataKi:  2.86E+3nMAssay Description:Binding affinity to hsst5 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096817((S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(propan...)
Affinity DataKi:  3.75E+3nMAssay Description:Binding affinity to hsst3 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096825((S)-6-Amino-2-{(S)-3-(1H-indol-3-yl)-2-[(1-isobuty...)
Affinity DataKi:  5.25E+3nMAssay Description:Binding affinity to hsst3 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096817((S)-6-Amino-2-((S)-3-(1H-indol-3-yl)-2-{[1-(propan...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to hsst5 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed