Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50035202
LigandPNGBDBM50098037(4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-pipe...)
Affinity DataIC50: 0.200nMAssay Description:Inhibitory activity against human Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098005(N-Isopropyl-2-(1-methyl-2-o-tolyl-1H-indol-3-yl)-N...)
Affinity DataIC50: 12nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098002(N-Isopropyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-N-...)
Affinity DataIC50: 15nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 20nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase 5 nM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098027(N-Isopropyl-N-pyridin-4-ylmethyl-2-(2-o-tolyl-1H-i...)
Affinity DataIC50: 31nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098039(N-Isopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4...)
Affinity DataIC50: 41nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 43nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098022(N-Cyclobutyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-...)
Affinity DataIC50: 44nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098030(N-Cyclopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin...)
Affinity DataIC50: 45nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098034(2-[2-(2-Chloro-phenyl)-1H-indol-3-yl]-N-isopropyl-...)
Affinity DataIC50: 46nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 47nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 54nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098035(N-Isopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-3...)
Affinity DataIC50: 58nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 65nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50366777(CHEMBL1788269)
Affinity DataIC50: 77nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 106nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098018(N-Furan-3-ylmethyl-N-isopropyl-2-(2-phenyl-1H-indo...)
Affinity DataIC50: 110nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098006(N-(2-Cyano-ethyl)-N-cyclopropyl-2-(2-phenyl-1H-ind...)
Affinity DataIC50: 123nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098025(N-Cyclobutyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-...)
Affinity DataIC50: 160nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098016(N-Cyclopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin...)
Affinity DataIC50: 171nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098020(2-[2-(3-Chloro-phenyl)-1H-indol-3-yl]-N-isopropyl-...)
Affinity DataIC50: 172nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098023(N-(2-Cyano-ethyl)-N-cyclopropyl-2-(1-methyl-2-phen...)
Affinity DataIC50: 182nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 190nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferase with 5 nM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 230nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 230nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098010(N-Isopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyrimidin...)
Affinity DataIC50: 232nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098009(N-Furan-2-ylmethyl-N-isopropyl-2-(2-phenyl-1H-indo...)
Affinity DataIC50: 241nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098019(N-Isopropyl-N-(2-methyl-2H-pyrazol-3-ylmethyl)-2-(...)
Affinity DataIC50: 245nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098003(N-Ethyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylm...)
Affinity DataIC50: 250nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098014(N-(Cyano-methyl-methyl)-2-(2-phenyl-1H-indol-3-yl)...)
Affinity DataIC50: 380nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098036(N-Isopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyrazin-2...)
Affinity DataIC50: 400nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098037(4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-pipe...)
Affinity DataIC50: 517nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098011(N-Isopropyl-N-(1-methyl-1H-pyrazol-4-ylmethyl)-2-(...)
Affinity DataIC50: 527nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098028(N-Isopropyl-N-(1-methyl-1H-pyrazol-3-ylmethyl)-2-(...)
Affinity DataIC50: 568nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098040(2-[1-(2-Bromo-benzyl)-1H-indol-3-yl]-N-isopropyl-N...)
Affinity DataIC50: 572nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098015(N-Isopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-2...)
Affinity DataIC50: 684nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098045(N-(2-Cyano-ethyl)-N-cyclopropyl-2-(2-o-tolyl-1H-in...)
Affinity DataIC50: 712nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098002(N-Isopropyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-N-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of HDJ-2 farnesylation in PSN-1 cells with 100 nM GGT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098005(N-Isopropyl-2-(1-methyl-2-o-tolyl-1H-indol-3-yl)-N...)
Affinity DataEC50:  1.06E+3nMAssay Description:Inhibition of HDJ-2 farnesylation in PSN-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098002(N-Isopropyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-N-...)
Affinity DataEC50:  1.33E+3nMAssay Description:Inhibition of HDJ-2 farnesylation in PSN-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098021(N-Isopropyl-2-[2-(2-methoxy-phenyl)-1H-indol-3-yl]...)
Affinity DataIC50: 1.37E+3nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098044(N-Isobutyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-2-...)
Affinity DataIC50: 1.50E+3nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098032(2-[2-(2-Chloro-phenyl)-1H-indol-3-yl]-N-(2-cyano-e...)
Affinity DataIC50: 1.63E+3nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098013(2-[1-(4-Bromo-benzyl)-1H-indol-3-yl]-N-isopropyl-N...)
Affinity DataIC50: 1.74E+3nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098002(N-Isopropyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-N-...)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of K-Ras farnesylation in PSN-1 cells with 100 nM GGT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098002(N-Isopropyl-2-(1-methyl-2-phenyl-1H-indol-3-yl)-N-...)
Affinity DataEC50:  1.98E+3nMAssay Description:Inhibition of HDJ-2 farnesylation in PSN-1 cells at without GGT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098004(2-[1-(3-Bromo-benzyl)-1H-indol-3-yl]-N-isopropyl-N...)
Affinity DataIC50: 2.15E+3nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098042(N-Isobutyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-3-...)
Affinity DataIC50: 2.48E+3nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098029(2-(2-Phenyl-1H-indol-3-yl)-N,N-bis-pyridin-3-ylmet...)
Affinity DataIC50: 2.73E+3nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
LigandPNGBDBM50098012(2-(1-Ethyl-2-phenyl-1H-indol-3-yl)-N-isopropyl-N-p...)
Affinity DataIC50: 3.80E+3nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
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