Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50037010
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095523([(S)-2-methyl-1-((S)-2-{(S)-2-methyl-1-[5-(3-methy...)
Affinity DataKi:  0.0250nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095526([2-Methyl-1-(2-{2-methyl-1-[5-(3-methyl-benzyl)-[1...)
Affinity DataKi:  0.490nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095530((S)-2-(5-amino-2-(4-fluorophenyl)-6-oxopyrimidin-1...)
Affinity DataKi:  0.520nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095521((S)-2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimi...)
Affinity DataKi:  0.640nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095519((S)-2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimi...)
Affinity DataKi:  1.18nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095525((S)-2-(5-amino-2-(4-fluorophenyl)-6-oxopyrimidin-1...)
Affinity DataKi:  1.37nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098818(2-{3-Methyl-2-[(pyridine-3-carbonyl)-amino]-butyry...)
Affinity DataKi:  1.66nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098833(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  2.25nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098827(2-(5-Amino-6-oxo-2-phenyl-6H-pyrimidin-1-yl)-N-{2-...)
Affinity DataKi:  2.55nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098817(2-[2-(4-Fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-N-...)
Affinity DataKi:  3.35nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095527((S)-2-(5-amino-6-oxo-2-phenylpyrimidin-1(6H)-yl)-N...)
Affinity DataKi:  3.59nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098830(1-{3-Methyl-2-[(pyridine-3-carbonyl)-amino]-butyry...)
Affinity DataKi:  5.10nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095520((S)-2-(5-amino-2-(4-fluorophenyl)-6-oxopyrimidin-1...)
Affinity DataKi:  6.38nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098823(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  6.76nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098826(2-(5-Amino-6-oxo-2-phenyl-6H-pyrimidin-1-yl)-N-{2-...)
Affinity DataKi:  8.75nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098821(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  10.7nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095529(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  11.8nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098815(1-(2-Methanesulfonylamino-3-methyl-butyryl)-pyrrol...)
Affinity DataKi:  12nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095522(ONO-6818 | 2-(5-amino-6-oxo-2-phenylpyrimidin-1(6H...)
Affinity DataKi:  12.2nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098824(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  13.9nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098819(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  14nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095524(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  15.3nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098816(2-(5-Amino-6-oxo-2-pyridin-3-yl-6H-pyrimidin-1-yl)...)
Affinity DataKi:  16.6nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098828(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  21.2nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098832(N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2...)
Affinity DataKi:  23.5nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098822(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  24.8nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098814(N-{2-Methyl-1-[5-(1-methyl-cyclopropyl)-[1,3,4]oxa...)
Affinity DataKi:  26.4nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098812(2-[2-(4-Fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-N-...)
Affinity DataKi:  43.8nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50095518((S)-N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbony...)
Affinity DataKi:  44.3nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098831(N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2...)
Affinity DataKi:  57.8nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098834(1-(3H-Imidazole-4-carbonyl)-2,3-dihydro-1H-indole-...)
Affinity DataKi:  79.7nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50036093(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  101nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098820(2-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2...)
Affinity DataKi:  114nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098836(N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2...)
Affinity DataKi:  163nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098837(2-(3H-Imidazole-4-carbonyl)-1,2,3,4-tetrahydro-iso...)
Affinity DataKi:  309nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098813(3-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2...)
Affinity DataKi:  725nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098825(N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2...)
Affinity DataKi:  730nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098829(N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2...)
Affinity DataKi:  836nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Cortech

Curated by ChEMBL
LigandPNGBDBM50098835(N-[1-(5-tert-Butyl-[1,3,4]oxadiazole-2-carbonyl)-2...)
Affinity DataKi:  4.28E+3nMAssay Description:Binding constant derived from inhibition of elastase catalyzed hydrolysis of synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed