Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50010876
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM20625(CHEMBL411 | Stilbestrol | 4-[(3E)-4-(4-hydroxyphen...)
Affinity DataEC50:  0.00700nMAssay Description:In vitro agonist effect on estrogen receptor alpha transcriptional activation in MCF-7 cells at 10 pMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 0.720nMAssay Description:In vitro antagonist effect on estrogen receptor alpha transcriptional activation in MCF-7 cells against 10 pM 17-beta-estradiolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099587(US8815934, No. 107 | CHEMBL44426 | US8815934, No. ...)
Affinity DataIC50: 1.5nMAssay Description:In vitro antagonist effect on estrogen receptor alpha transcriptional activation in MCF-7 cells against 10 pM 17-beta-estradiolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM20625(CHEMBL411 | Stilbestrol | 4-[(3E)-4-(4-hydroxyphen...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099585(1-[4-(2-Azepan-1-yl-ethoxy)-benzyl]-2-(4-hydroxy-p...)
Affinity DataIC50: 3.70nMAssay Description:In vitro antagonist effect on estrogen receptor alpha transcriptional activation in MCF-7 cells against 10 pM 17-beta-estradiolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM20625(CHEMBL411 | Stilbestrol | 4-[(3E)-4-(4-hydroxyphen...)
Affinity DataIC50: 4nMAssay Description:In vitro inhibitory concentration against [3H]17-beta-estradiol binding to human estrogen receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099587(US8815934, No. 107 | CHEMBL44426 | US8815934, No. ...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099585(1-[4-(2-Azepan-1-yl-ethoxy)-benzyl]-2-(4-hydroxy-p...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099586(ZK-119010 | 2-(4-Hydroxy-phenyl)-3-methyl-1-(6-pyr...)
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of [3H]17-beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099587(US8815934, No. 107 | CHEMBL44426 | US8815934, No. ...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory concentration against [3H]17-beta-estradiol binding to human estrogen receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM19441(Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...)
Affinity DataIC50: 43nMAssay Description:In vitro inhibitory concentration against [3H]17-beta-estradiol binding to human estrogen receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099586(ZK-119010 | 2-(4-Hydroxy-phenyl)-3-methyl-1-(6-pyr...)
Affinity DataIC50: 69nMAssay Description:In vitro antagonist effect on estrogen receptor alpha transcriptional activation in MCF-7 cells against 10 pM 17-beta-estradiolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099585(1-[4-(2-Azepan-1-yl-ethoxy)-benzyl]-2-(4-hydroxy-p...)
Affinity DataIC50: 85nMAssay Description:In vitro inhibitory concentration against [3H]17-beta-estradiol binding to human estrogen receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099586(ZK-119010 | 2-(4-Hydroxy-phenyl)-3-methyl-1-(6-pyr...)
Affinity DataIC50: 242nMAssay Description:In vitro inhibitory concentration against [3H]17-beta-estradiol binding to human estrogen receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed