Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50010915
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100105(2-(5-Bromo-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-N...)
Affinity DataIC50: 49nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100101(2-(5-Bromo-1-cyclopropylmethyl-2,2-dioxo-1,4-dihyd...)
Affinity DataIC50: 69nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100094(2-(5-Bromo-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-ben...)
Affinity DataIC50: 98nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100102(2-(5-Chloro-1-cyclopropylmethyl-2,2-dioxo-1,4-dihy...)
Affinity DataIC50: 110nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: 120nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100096(2-(2,2-Dioxo-5-trifluoromethyl-1,4-dihydro-2H-2lam...)
Affinity DataIC50: 130nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100107(N-Hydroxy-2-(2-oxo-5-trifluoromethyl-1,4-dihydro-2...)
Affinity DataIC50: 230nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100108(2-[5-Chloro-2,2-dioxo-1-(3-phenyl-propyl)-1,4-dihy...)
Affinity DataIC50: 290nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 310nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 460nMAssay Description:Inhibition of Collagenase-3, matrix metalloptroteinase-13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Collagenase-3, matrix metalloptroteinase-13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100100(2-(1-Butyl-5-chloro-2,2-dioxo-1,4-dihydro-2H-2lamb...)
Affinity DataIC50: 590nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100104(2-(2,2-Dioxo-1,4-dihydro-2H-2lambda*6*-benzo[1,2,6...)
Affinity DataIC50: 760nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100099(2-(5-Fluoro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 870nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100103(2-(5-Fluoro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: 870nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100098(N-Hydroxy-2-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100106(2-(1-Benzyl-5-chloro-2,2-dioxo-1,4-dihydro-2H-2lam...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition against endothelin-converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition against endothelin-converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100093((5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-ac...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human macrophage elastase, matrix metalloproteinase-12 (MMP-12).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100097(2-(5-Chloro-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human macrophage elastase, matrix metalloproteinase-12 (MMP-12).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed