Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50010935
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
Central Research Institute

Curated by ChEMBL
LigandPNGBDBM50006412(Pravastatin | Eptastatin Sodium | (3R,5R)-3,5-dihy...)
Affinity DataIC50: 4.20nMAssay Description:In vitro HMG-CoA reductase inhibitory activity to inhibit sterol synthesis in cell free system in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Human)
Central Research Institute

Curated by ChEMBL
LigandPNGBDBM50006412(Pravastatin | Eptastatin Sodium | (3R,5R)-3,5-dihy...)
Affinity DataIC50: 1.37E+3nMAssay Description:In vitro HMG-CoA reductase inhibitory activity to inhibit cellular steroidgenesis in Hep G2 cells (human hepatoma cell line)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed