Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50023563
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242353(5-thia-8,11,14,17-eicosatetraenoic acid | CHEMBL46...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242349(5,8,11,14,17-EICOSAPENTAENOIC ACID | 5Z,8Z,11Z,14Z...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50210259(all-cis-docosa-4,7,10,13,16,19-hexaenoic acid | Do...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240347((Z,Z,Z)-9,12,15-octadecatrienoic acid | cis,cis,ci...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242349(5,8,11,14,17-EICOSAPENTAENOIC ACID | 5Z,8Z,11Z,14Z...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50210259(all-cis-docosa-4,7,10,13,16,19-hexaenoic acid | Do...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242353(5-thia-8,11,14,17-eicosatetraenoic acid | CHEMBL46...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242357((5E,9Z,12Z,15Z,18Z)-3-oxaheneicosa-5,9,12,15,18-pe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242355((7E,11Z,14Z,17Z)-5-thiaeicosa-7,11,14,17-tetraenoi...)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242352(3-thia-6,9,12,15-octadecatetraenoic acid | CHEMBL4...)
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240347((Z,Z,Z)-9,12,15-octadecatrienoic acid | cis,cis,ci...)
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22231(CHEMBL267476 | (9Z,12Z)-octadeca-9,12-dienoic acid...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242355((7E,11Z,14Z,17Z)-5-thiaeicosa-7,11,14,17-tetraenoi...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242352(3-thia-6,9,12,15-octadecatetraenoic acid | CHEMBL4...)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM22231(CHEMBL267476 | (9Z,12Z)-octadeca-9,12-dienoic acid...)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242357((5E,9Z,12Z,15Z,18Z)-3-oxaheneicosa-5,9,12,15,18-pe...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150484(CHEMBL8659 | oleaic acid | Octadec-9-enoic acid | ...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | Hexadecanoic acid anion | H...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242348(pentadecanoic acid | CHEMBL460025)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50147581(n-tetradecanoic acid | tetradecoic acid | myristic...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242354(3-oxa-6,9,12,15-octadecatetraenoic acid | CHEMBL46...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242356((5E,9Z,12Z,15Z)-3-oxaoctadeca-5,9,12,15-tetraenoic...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of sheep COX2-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50150484(CHEMBL8659 | oleaic acid | Octadec-9-enoic acid | ...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240485(stearic acid | 18:0 | C18:0 | CH3-[CH2]16-COOH | O...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | Hexadecanoic acid anion | H...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242348(pentadecanoic acid | CHEMBL460025)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50147581(n-tetradecanoic acid | tetradecoic acid | myristic...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242354(3-oxa-6,9,12,15-octadecatetraenoic acid | CHEMBL46...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Bovine)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50242356((5E,9Z,12Z,15Z)-3-oxaoctadeca-5,9,12,15-tetraenoic...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of bovine COX1-mediated prostaglandin biosynthesis using [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed