Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50041037
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421498(ORG-24669 | CHEMBL59858)
Affinity DataIC50: 100nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataIC50: 126nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421509(ORG-24915 | CHEMBL58459)
Affinity DataIC50: 151nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421499(ORG-24645 | CHEMBL302908)
Affinity DataIC50: 251nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421489(ORG-24461 | CHEMBL59821)
Affinity DataIC50: 316nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421497(ORG-24658 | CHEMBL64750)
Affinity DataIC50: 398nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421502(ORG-24835 | CHEMBL61860)
Affinity DataIC50: 447nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421495(ORG-24706 | CHEMBL60441)
Affinity DataIC50: 501nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421491(ORG-24668 | CHEMBL60445)
Affinity DataIC50: 501nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421500(ORG-24914 | CHEMBL62571)
Affinity DataIC50: 977nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421490(ORG-24750 | CHEMBL64154)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421503(ORG-24667 | CHEMBL64451)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421504(ORG-24747 | CHEMBL408571)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421501(ORG-24642 | CHEMBL304470)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421492(ORG-24597 | CHEMBL64272)
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421505(ORG-24641 | CHEMBL60948)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421496(ORG-24660 | CHEMBL64717)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421508(ORG-24836 | CHEMBL61270)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421494(ORG-24730 | CHEMBL293691)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421493(ORG-24520 | CHEMBL64234)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421507(ORG-24629 | CHEMBL64028)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50403865(ORG-24628 | CHEMBL64102)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50403866(ORG-24872 | CHEMBL60614)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]glycine uptake using CHO cells transfected with GlyT-1b transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Alpha-2C adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Beta-1 adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:The compound was tested for the binding affinity towards Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Beta-2 adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Dopamine receptor D4 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards serotonin 5-hydroxytryptamine 7 receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Dopamine receptor D2S was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards serotonin 5-hydroxytryptamine 2C receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards Binding affinity towards Alpha-1A adrenergic receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards serotonin 5-hydroxytryptamine 6 receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM50421506(ORG-24598 | CHEMBL61861)
Affinity DataKi: <1.00E+4nMAssay Description:Binding affinity of compound towards serotonin 5-hydroxytryptamine 2A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed