Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 647
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4780(N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-...)
Affinity DataIC50: 0.170nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4791((2E)-3-({4-[(3-bromophenyl)amino]quinazolin-6-yl}c...)
Affinity DataIC50: 0.370nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4808(N-(3-Bromophenyl)-6-(vinylsulfonyl)pyrido[3,4-d]py...)
Affinity DataIC50: 0.430nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4798((2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-N...)
Affinity DataIC50: 0.440nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4783((2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrim...)
Affinity DataIC50: 0.5nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4596((2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}bu...)
Affinity DataIC50: 0.550nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4802((2E)-N1-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-...)
Affinity DataIC50: 0.560nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4804((2E)-N1-[4-(3-Chloro-4-fluoroanilino)pyrido[3,4-d]...)
Affinity DataIC50: 0.610nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4785((2Z)-N-[4-(3-Bromoanilino)-6-pyrido[3,4-d]pyrimidi...)
Affinity DataIC50: 0.690nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4567(CHEMBL285063 | N-{4-[(3-bromophenyl)amino]quinazol...)
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4800((2E)-N1-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-...)
Affinity DataIC50: 0.730nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4805(N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-...)
Affinity DataIC50: 0.760nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4801((2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrim...)
Affinity DataIC50: 0.810nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4777(N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-...)
Affinity DataIC50: 0.910nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4799((2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrim...)
Affinity DataIC50: 1.10nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4787((2E)-N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6...)
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4595(6-Substituted 4-Anilinoquinazoline 9 | N-{4-[(3-br...)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4790((2E)-N-[4-(3-Bromoanilino)-6-quinazolinyl]-4-oxo-2...)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4806(N-[4-(3-Bromoanilino)-6-quinazolinyl]ethylenesulfo...)
Affinity DataIC50: 1.40nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4803((2E)-N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrim...)
Affinity DataIC50: 1.45nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataIC50: 1.5nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4793(ethyl (2E)-3-({4-[(3-bromophenyl)amino]pyrido[3,4-...)
Affinity DataIC50: 1.5nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4781(N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-...)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4788(N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}buta-2,...)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4786((2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4...)
Affinity DataIC50: 1.75nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4797(3-(dimethylamino)propyl (2E)-3-({4-[(3-bromophenyl...)
Affinity DataIC50: 2.40nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4795(N-{4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin-...)
Affinity DataIC50: 2.70nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4792(ethyl (2E)-3-({4-[(3-bromophenyl)amino]quinazolin-...)
Affinity DataIC50: 2.70nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4796(N-[4-(3-Bromoanilino)-6-quinazolinyl]-N-[3-(4-morp...)
Affinity DataIC50: 3.30nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4794(N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]-...)
Affinity DataIC50: 4.20nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4809(N-(3-Bromophenyl)-6-(vinylsulfinyl)pyrido[3,4-d]py...)
Affinity DataIC50: 4.60nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4789((2E)-N-[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6...)
Affinity DataIC50: 9.10nMpH: 7.4 T: 2°CAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM4807(2-{[4-(3-Bromoanilino)pyrido[3,4-d]pyrimidin-6-yl]...)
Affinity DataIC50: 93.5nMAssay Description:Enzyme assays for IC50 determinations were performed in 96-well filter plates. IC50 is the inhibitor concentration which inhibits 50% of kinase activ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2005
Entry Details Article
PubMed