Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50011179
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103243(4-{2-[2-(2-Acetylamino-3-carboxy-propionylamino)-p...)
Affinity DataKi:  200nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103235(5-[2-(2-{2-[2-(2-Acetylamino-3-carboxy-propionylam...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103240(4-Carbamoyl-4-{[6-(difluoro-phosphono-methyl)-naph...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103227(6-(Difluoro-phosphono-methyl)-naphthalene-2-carbox...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103232(Naphthalene-1,6-dicarboxylic acid | CHEMBL420818)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103238(3-Carboxymethoxy-naphthalene-2,7-dicarboxylic acid...)
Affinity DataKi:  2.50E+5nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103234(2-Carboxymethoxy-naphthalene-1,6-dicarboxylic acid...)
Affinity DataKi:  9.00E+5nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103236(2-Methoxy-naphthalene-1,6-dicarboxylic acid 6-meth...)
Affinity DataIC50: 2.80E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103231(Naphthalene-2,7-dicarboxylic acid | CHEMBL98615)
Affinity DataKi: >3.20E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103244(6-(1-Carbamoyl-3-carboxy-propylcarbamoyl)-2-carbox...)
Affinity DataIC50: 3.80E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103242(naphthalene-1,3,6-trisulfonate(3-) | CHEMBL316894 ...)
Affinity DataKi: >4.00E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM36149(CHEMBL319726 | 2,6-naphthalenedisulfonate)
Affinity DataIC50: 4.00E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103226(dipotassium naphthalene-2,6-dicarboxylate | CHEMBL...)
Affinity DataIC50: 4.00E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103241(6-Carboxymethoxy-naphthalene-2-carboxylic acid | C...)
Affinity DataIC50: 9.40E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103239(6-(Carboxy-difluoro-methoxy)-naphthalene-2-carboxy...)
Affinity DataIC50: 9.40E+6nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103228(2-Hydroxy-naphthalene-1,6-dicarboxylic acid | CHEM...)
Affinity DataIC50: 1.20E+7nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103230(2-Methoxy-naphthalene-1,6-dicarboxylic acid | CHEM...)
Affinity DataIC50: 2.00E+7nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103237(disodium naphthalene-1,5-disulfonate | CHEMBL95668)
Affinity DataIC50: 2.80E+7nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50103229(5-Methanesulfonylamino-naphthalene-2-sulfonic acid...)
Affinity DataIC50: 2.90E+7nMAssay Description:Inhibitory activity against human Protein-tyrosinephosphatase 1B (PTP1B)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed