Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50011306
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104967(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-[2-(4-metho...)
Affinity DataKi:  0.450nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104969(N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PR...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104969(N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PR...)
Affinity DataKi: <1nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104969(N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PR...)
Affinity DataKi: <1nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104969(N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PR...)
Affinity DataKi: <1nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104967(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-[2-(4-metho...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104967(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-[2-(4-metho...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104968(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(4-meth...)
Affinity DataKi:  9.20nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104967(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-[2-(4-metho...)
Affinity DataKi:  11nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104962(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  37nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104968(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(4-meth...)
Affinity DataKi:  52nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104966(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-(2-hydroxy-...)
Affinity DataKi:  70nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104962(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  73nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104962(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  82nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104962(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  162nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104966(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-(2-hydroxy-...)
Affinity DataKi:  166nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataKi:  171nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104968(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(4-meth...)
Affinity DataKi:  203nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104971(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  303nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104966(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-(2-hydroxy-...)
Affinity DataKi:  408nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104966(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-(2-hydroxy-...)
Affinity DataKi:  946nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104971(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  1.09E+3nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104968(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(4-meth...)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104970(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(3-meth...)
Affinity DataKi:  1.19E+3nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104965((2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R...)
Affinity DataKi:  1.51E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104971(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104965((2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R...)
Affinity DataKi:  3.32E+3nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104971(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-isobuty...)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataKi:  4.47E+3nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataKi:  6.30E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104970(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(3-meth...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104965((2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R...)
Affinity DataKi:  8.60E+3nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104964(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-indan-1-yl-...)
Affinity DataKi:  1.53E+4nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104970(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(3-meth...)
Affinity DataKi:  1.55E+4nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104964(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-indan-1-yl-...)
Affinity DataKi:  2.12E+4nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104972(2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2...)
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104965((2R)-N~4~-hydroxy-2-(3-hydroxybenzyl)-N~1~-[(1S,2R...)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104964(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-indan-1-yl-...)
Affinity DataKi:  3.16E+4nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104963(2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydr...)
Affinity DataKi:  3.32E+4nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104972(2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104972(2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2...)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104972(2-Benzo[1,3]dioxol-5-ylmethyl-N*4*-hydroxy-N*1*-(2...)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104964(N*4*-Hydroxy-2-(4-hydroxy-benzyl)-N*1*-indan-1-yl-...)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104970(N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(3-meth...)
Affinity DataKi:  9.55E+4nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed