Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 617
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4560(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-[3-(4-hy...)
Affinity DataIC50: 0.640nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4557(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 0.760nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4553(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-[3-(4-et...)
Affinity DataIC50: 0.770nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4543(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4544(4-[(2-bromo-4-chloro-5-methoxyphenyl)amino]-6-meth...)
Affinity DataIC50: 0.950nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4556(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 1.10nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4555(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 1.10nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4547(4-[(2-Chloro-5-methoxy-4-methylphenyl)amino]-6-met...)
Affinity DataIC50: 1.10nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4559(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 1.20nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 1.20nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4545(4-[(4-Chloro-5-methoxy-2-methylphenyl)amino]-6-met...)
Affinity DataIC50: 1.20nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4550(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 1.30nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4558(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 1.40nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4554(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 1.40nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4542(4-[(2-chloro-5-methoxyphenyl)amino]-6-methoxy-7-[3...)
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4546(6-methoxy-4-[(5-methoxy-2,4-dimethylphenyl)amino]-...)
Affinity DataIC50: 1.70nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4562(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 1.90nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4563(4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[3-(1H-i...)
Affinity DataIC50: 2.10nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4549(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 2.30nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4565(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-7-{3-[((2-...)
Affinity DataIC50: 2.30nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4551(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 2.5nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4534(4-[(2-Chloro-5-ethoxy-4-methylphenyl)amino]-6,7-di...)
Affinity DataIC50: 2.90nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4564(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 3nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4530(4-[(2-bromo-4-chloro-5-methoxyphenyl)amino]-6,7-di...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4520(4-Phenylamino-3-quinolinecarbonitrile deriv. 2a | ...)
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4531(CHEMBL127331 | 4-[(4-Chloro-5-methoxy-2-methylphen...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4525(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6,7-dimeth...)
Affinity DataIC50: 4.30nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4536(6,7-dimethoxy-4-[(5-methoxy-2,4-dimethylphenyl)ami...)
Affinity DataIC50: 4.60nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4515(4-[(4-Chloro-2-iodophenyl)amino]-6,7-dimethoxy-3-q...)
Affinity DataIC50: 6.20nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4561(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 9.30nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4524(4-[(2-chloro-5-methoxyphenyl)amino]-6,7-dimethoxyq...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4548(4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-methoxy-...)
Affinity DataIC50: 28nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4492(CHEMBL101917 | 4-[(2,4-dichlorophenyl)amino]-6,7-d...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4529(4-[4-Chloro-2-fluoro-5-methoxyphenyl)amino]-6,7-di...)
Affinity DataIC50: 66nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4540(N-(2,4-dichloro-5-methoxyphenyl)-6,7-dimethoxyquin...)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4494(quinazoline deriv. 4a | (2,4-Dichlorophenyl)(6,7-d...)
Affinity DataIC50: 84nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4528(4-[(2,4-Dichloro-5-hydroxyphenyl)amino]-6,7-dimeth...)
Affinity DataIC50: 190nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4493(4-[(2,4-Dichlorophenyl)amino]-6,7-dimethoxyquinazo...)
Affinity DataIC50: 250nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4539(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6,7-dimeth...)
Affinity DataIC50: 390nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4526(4-[(2,4-Dichloro-5-ethoxyphenyl)amino]-6,7-dimetho...)
Affinity DataIC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4527(4-[(2,4-dichloro-5-propoxyphenyl)amino]-6,7-dimeth...)
Affinity DataIC50: 5.00E+3nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed