Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50036980
Target5-hydroxytryptamine receptor 1F(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  7.90nMAssay Description:In vitro effective concentration for inhibition of skolin-stimulated adenylate cyclase in cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataEC50:  6nMAssay Description:In vitro effective concentration for inhibition of skolin-stimulated adenylate cyclase in cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataEC50:  35nMAssay Description:In vitro effective concentration for inhibition of skolin-stimulated adenylate cyclase in cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106483(4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-indol-4...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106484(N-[3-(2-Dimethylamino-ethyl)-1H-indol-4-yl]-4-fluo...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  8.20nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1F receptor using [3H]-5-HT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50005835(Sumax | 3-[2-(dimethylamino)ethyl]-N-methylindole-...)
Affinity DataKi:  25.7nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1F receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  265nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1A receptor was determined using [3H]-5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  380nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 4 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  676nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 2B receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 2A receptor using [125I]DOI as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  1.06E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1B receptor using [3H]5-HT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  1.46E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  1.62E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1D receptor was determined using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  1.77E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 6 receptor using [3H]LSD as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity towards human 5-HT2C receptor was determined using [125I]- DOI as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi: >4.83E+3nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 1E receptor was determined using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity towards rat histamine H1 receptor was determined using [3H]pyrilamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi:  3.80E+4nMAssay Description:Binding affinity towards rat dopamine D2 receptor was determined using [3H]raclopride as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50106482(N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-y...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity towards rat dopamine receptor D1 was determined using [3H]SCH-23390 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed