Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50011474
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50002692(1-((2R,4S,5S)-4-Azido-5-hydroxymethyl-tetrahydro-f...)
Affinity DataEC50:  3nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50169035([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...)
Affinity DataEC50:  60nMAssay Description:Effective concentration required to inhibit HIV-1 induced cytopathicity by 50% in CEM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50106903({3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-but...)
Affinity DataEC50:  1.80E+3nMAssay Description:Effective concentration required to inhibit HIV-1 induced cytopathicity by 50% in CEM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403886(CHEMBL102269)
Affinity DataEC50: >2.00E+3nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50169035([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...)
Affinity DataIC50: 3.60E+3nMAssay Description:The compound was evaluated for inhibition of HIV-1 wild types GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403892(CHEMBL321135 | CHEMBL3142818)
Affinity DataEC50:  4.00E+3nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50024581(CHEMBL3142813)
Affinity DataEC50:  4.50E+3nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50106919({3-[3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-but...)
Affinity DataEC50:  4.50E+3nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403884(CHEMBL323339 | CHEMBL3142819)
Affinity DataEC50:  5.00E+3nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403893(CHEMBL107000 | CHEMBL3142820)
Affinity DataEC50: >1.00E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403895(CHEMBL608621)
Affinity DataEC50: >1.00E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403882(CHEMBL321101 | CHEMBL3142814)
Affinity DataEC50: >1.00E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403885(CHEMBL104540 | CHEMBL3142811)
Affinity DataEC50: >1.00E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403888(CHEMBL321344 | CHEMBL3142812)
Affinity DataEC50:  2.00E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403883(CHEMBL431822 | CHEMBL3142815)
Affinity DataEC50:  3.20E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50106919({3-[3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-but...)
Affinity DataIC50: 3.38E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 wild types GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50106919({3-[3-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-but...)
Affinity DataIC50: 4.74E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403891(CHEMBL105831 | CHEMBL3142816)
Affinity DataEC50: >5.00E+4nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403896(CHEMBL607754)
Affinity DataEC50:  1.17E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50024581(CHEMBL3142813)
Affinity DataIC50: 1.38E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 wild types GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50024581(CHEMBL3142813)
Affinity DataIC50: 1.58E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50106903({3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-but...)
Affinity DataIC50: 2.07E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 wild types GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403887(CHEMBL611868)
Affinity DataEC50: >2.50E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403889(CHEMBL318807)
Affinity DataEC50: >2.50E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403890(CHEMBL608622)
Affinity DataEC50: >2.50E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50403894(CHEMBL322101)
Affinity DataEC50: >2.50E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50106903({3-[4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-but...)
Affinity DataIC50: 3.35E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50169035([2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribo...)
Affinity DataIC50: 5.00E+5nMAssay Description:The compound was evaluated for inhibition of HIV-1 mutant GluL38-Lys recombinant reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed