Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50037072
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50059889(3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108776(4-(2-Amino-5-oxo-3,5-dihydro-imidazol-4-ylidene)-2...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM7491(4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108774(2-bromoaldisin | 2-Bromo-6,7-dihydro-1H,5H-pyrrolo...)
Affinity DataIC50: 539nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50363645(DEBROMOHYMENIALDISINE)
Affinity DataIC50: 824nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM59117(CHEMBL151430 | Hymenialdisine, 11b)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM59117(CHEMBL151430 | Hymenialdisine, 11b)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50108776(4-(2-Amino-5-oxo-3,5-dihydro-imidazol-4-ylidene)-2...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50220547(oroidin base | oroidin | 4,5-Dibromo-1H-pyrrole-2-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50363645(DEBROMOHYMENIALDISINE)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108773(4,5-dibromopyrrole-2-carboxamide | 4,5-Dibromo-1H-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108777(aldisin | 6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50108773(4,5-dibromopyrrole-2-carboxamide | 4,5-Dibromo-1H-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50108774(2-bromoaldisin | 2-Bromo-6,7-dihydro-1H,5H-pyrrolo...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM7491(4-[2-Amino-5-oxo-1,5-dihydro-imidazol-(4Z)-ylidene...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50108777(aldisin | 6,7-Dihydro-1H,5H-pyrrolo[2,3-c]azepine-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50220547(oroidin base | oroidin | 4,5-Dibromo-1H-pyrrole-2-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Utah

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase (MAPK)phosphorylation by activated MEK-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK1 phosphorylation by activated human recombinant RafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed