Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50037112
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0100nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha4-beta2 using +/-[3H]epibatidine as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110258(2-(6-Chloro-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha4-beta2 using +/-[3H]epibatidine as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110260(2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | 2-P...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha4-beta2 using +/-[3H]epibatidine as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110259(2-Pyrimidin-5-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha4-beta2 using +/-[3H]epibatidine as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  0.840nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha4-beta2 using +/-[3H]epibatidine as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110260(2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | 2-P...)
Affinity DataKi:  0.950nMAssay Description:Binding affinity to subtype Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50023330(Anatoxin-a | Anatoxin-A,(+) | CHEMBL25619 | 1-(9-a...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha4-beta2 using +/-[3H]epibatidine as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110258(2-(6-Chloro-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110262(2-Pyridazin-4-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  4nMAssay Description:Binding affinity to subtype Nicotinic acetylcholine receptor alpha-7 using [125I]-alpha-BTX as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeuronal acetylcholine receptor subunit beta-4(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110260(2-Pyridin-3-yl-9-aza-bicyclo[4.2.1]non-2-ene | 2-P...)
Affinity DataKi:  6.20nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110262(2-Pyridazin-4-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...)
Affinity DataKi: >10nMAssay Description:Binding affinity to subtype Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110259(2-Pyrimidin-5-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...)
Affinity DataKi:  11nMAssay Description:Binding affinity to subtype Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110263(2-Pyrazin-2-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)
Affinity DataKi:  12nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha4-beta2 using +/-[3H]epibatidine as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110258(2-(6-Chloro-pyridin-3-yl)-9-aza-bicyclo[4.2.1]non-...)
Affinity DataKi:  12nMAssay Description:Binding affinity to subtype Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110262(2-Pyridazin-4-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...)
Affinity DataKi:  19nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha4-beta2 using +/-[3H]epibatidine as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50023330(Anatoxin-a | Anatoxin-A,(+) | CHEMBL25619 | 1-(9-a...)
Affinity DataKi:  19nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110259(2-Pyrimidin-5-yl-9-aza-bicyclo[4.2.1]non-2-ene | C...)
Affinity DataKi:  20nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  73nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50023330(Anatoxin-a | Anatoxin-A,(+) | CHEMBL25619 | 1-(9-a...)
Affinity DataKi:  90nMAssay Description:Binding affinity to subtype Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  130nMAssay Description:Binding affinity to subtype Nicotinic acetylcholine receptor alpha-7 using [125I]-alpha-BTX as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110263(2-Pyrazin-2-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)
Affinity DataKi:  250nMAssay Description:Binding affinity to subtype Nicotinic acetylcholine receptor alpha7 using [3H]-MLA as radioligand in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-4(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50110263(2-Pyrazin-2-yl-9-aza-bicyclo[4.2.1]non-2-ene | CHE...)
Affinity DataKi:  259nMAssay Description:Binding affinity to Nicotinic acetylcholine receptor alpha3-beta4 using +/-[3H]epibatidine as radioligand in pig adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed