Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 1893
TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  0.100nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM14832(4-[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thi...)
Affinity DataKd:  180nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM14831(diaryl urea compound 2 | 3-(3-tert-butyl-1-methyl-...)
Affinity DataKd:  1.16E+3nMpH: 7.0 T: 2°CAssay Description:The exchange curve assays were run as two half-reactions using an SLM Aminco Bowman Series 2 model SQ-340 fluorescence detector. In the first half re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)