Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50037120
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110994(4-[2-Methyl-4-(5-methyl-thiophen-2-yl)-oxazol-5-yl...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110998(2-Fluoro-4-[2-methyl-4-(5-methyl-thiophen-2-yl)-ox...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111000(2-Fluoro-4-[4-(4-fluoro-phenyl)-2-methyl-oxazol-5-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107527(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfo...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110999(JTE-522 | CHEMBL34913 | 4-(4-Cyclohexyl-2-methyl-o...)
Affinity DataIC50: 85nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110995(4-(4-Cyclohexyl-2-ethyl-oxazol-5-yl)-2-fluoro-benz...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111004(4-(4-Cyclohexyl-2-isopropyl-oxazol-5-yl)-2-fluoro-...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110996(2-Amino-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-benz...)
Affinity DataIC50: 930nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110994(4-[2-Methyl-4-(5-methyl-thiophen-2-yl)-oxazol-5-yl...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111003(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methyl-ben...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107528(4-[4-(4-Fluoro-phenyl)-2-methyl-oxazol-5-yl]-benze...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110993(2-Chloro-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-ben...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111002(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-hydroxy-be...)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110998(2-Fluoro-4-[2-methyl-4-(5-methyl-thiophen-2-yl)-ox...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111004(4-(4-Cyclohexyl-2-isopropyl-oxazol-5-yl)-2-fluoro-...)
Affinity DataIC50: 2.97E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111000(2-Fluoro-4-[4-(4-fluoro-phenyl)-2-methyl-oxazol-5-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110995(4-(4-Cyclohexyl-2-ethyl-oxazol-5-yl)-2-fluoro-benz...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107527(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfo...)
Affinity DataIC50: 4.75E+4nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111001(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methoxy-be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111002(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-hydroxy-be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110996(2-Amino-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-benz...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110993(2-Chloro-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-ben...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111001(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methoxy-be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50110999(JTE-522 | CHEMBL34913 | 4-(4-Cyclohexyl-2-methyl-o...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50111003(4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methyl-ben...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human purified Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed