Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 50012179
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115725(3-(1-Indol-1-yl-3,4-dioxo-3,4-dihydro-naphthalen-2...)
Affinity DataIC50: 270nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115722(4-Cyclohexyl-[1,2]naphthoquinone | CHEMBL58737)
Affinity DataIC50: 320nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115756(3-(5,6-Dioxo-8-phenyl-5,6-dihydro-naphthalen-2-yl)...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115733(3-(3,4-Dioxo-1-phenyl-3,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50: 430nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115766(4-(4-Hydroxy-phenyl)-[1,2]naphthoquinone | CHEMBL5...)
Affinity DataIC50: 440nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115760(4-(2,5-Difluoro-phenyl)-[1,2]naphthoquinone | CHEM...)
Affinity DataIC50: 500nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115721(3-(3,4-Dioxo-1-phenyl-3,4-dihydro-naphthalen-2-yl)...)
Affinity DataIC50: 610nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115739([4-(1-Indol-1-yl-3,4-dioxo-3,4-dihydro-naphthalen-...)
Affinity DataIC50: 650nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115740((7,8-Dioxo-5-phenyl-7,8-dihydro-naphthalen-1-yl)-c...)
Affinity DataIC50: 650nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115746(3-[7-(2-Methoxycarbonyl-ethyl)-3,4-dioxo-1-phenyl-...)
Affinity DataIC50: 680nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50099778(4-Phenyl-[1,2]naphthoquinone | CHEMBL51447)
Affinity DataIC50: 840nMAssay Description:In vitro inhibitory activity against recombinant human CD45 using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50099778(4-Phenyl-[1,2]naphthoquinone | CHEMBL51447)
Affinity DataIC50: 860nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115763(7-Pentyloxy-4-phenyl-[1,2]naphthoquinone | CHEMBL5...)
Affinity DataIC50: 920nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115755(3-(8-Indol-1-yl-5,6-dioxo-5,6-dihydro-naphthalen-2...)
Affinity DataIC50: 920nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115751(3-[1-Indol-1-yl-6-(2-methoxycarbonyl-ethyl)-3,4-di...)
Affinity DataIC50: 940nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115761(4-[2-(3,4-Dioxo-1-phenyl-3,4-dihydro-naphthalen-2-...)
Affinity DataIC50: 1.01E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115728([4-(1-Indol-1-yl-3,4-dioxo-3,4-dihydro-naphthalen-...)
Affinity DataIC50: 1.01E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115729([4-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-phenoxy...)
Affinity DataIC50: 1.07E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115737(4-(1H-Indol-3-yl)-[1,2]naphthoquinone | CHEMBL6070...)
Affinity DataIC50: 1.13E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115727(4-(2-Nitro-phenyl)-[1,2]naphthoquinone | CHEMBL592...)
Affinity DataIC50: 1.17E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115744((7,8-Dioxo-5-phenyl-7,8-dihydro-naphthalen-1-yl)-c...)
Affinity DataIC50: 1.34E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115765(4-Benzyl-[1,2]naphthoquinone | CHEMBL292386)
Affinity DataIC50: 1.42E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115735([4-(3,4-Dioxo-1-phenyl-3,4-dihydro-naphthalen-2-yl...)
Affinity DataIC50: 1.48E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115748([4-(3,4-Dioxo-1-phenyl-3,4-dihydro-naphthalen-2-yl...)
Affinity DataIC50: 1.54E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115731(4-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-benzoic ...)
Affinity DataIC50: 1.54E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115738(4-(2-Hydroxy-phenyl)-[1,2]naphthoquinone | CHEMBL6...)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM22851(1,2-dihydronaphthalene-1,2-dione | 1,2-naphthoquin...)
Affinity DataIC50: 1.64E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115731(4-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-benzoic ...)
Affinity DataIC50: 1.65E+3nMAssay Description:In vitro inhibitory activity against recombinant human CD45 using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115737(4-(1H-Indol-3-yl)-[1,2]naphthoquinone | CHEMBL6070...)
Affinity DataIC50: 1.95E+3nMAssay Description:In vitro inhibitory activity against recombinant human Cdc25B using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115743(7-Methoxy-4-phenyl-[1,2]naphthoquinone | CHEMBL587...)
Affinity DataIC50: 2.04E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115764(2-(5-Indol-1-yl-7,8-dioxo-7,8-dihydro-naphthalen-2...)
Affinity DataIC50: 2.07E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115731(4-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-benzoic ...)
Affinity DataIC50: 2.13E+3nMAssay Description:In vitro inhibitory activity against recombinant human Cdc25B using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115749([2-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-phenoxy...)
Affinity DataIC50: 2.15E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115758([1,1']Binaphthalenyl-3,4-dione | CHEMBL59240)
Affinity DataIC50: 2.15E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115757((7,8-Dioxo-5-phenyl-7,8-dihydro-naphthalen-2-yl)-c...)
Affinity DataIC50: 2.25E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50099778(4-Phenyl-[1,2]naphthoquinone | CHEMBL51447)
Affinity DataIC50: 2.49E+3nMAssay Description:In vitro inhibitory activity against recombinant human LAR using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115762(2-(7,8-Dioxo-5-phenyl-7,8-dihydro-naphthalen-2-ylo...)
Affinity DataIC50: 2.54E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115741(3-Pentyloxy-4-phenyl-[1,2]naphthoquinone | CHEMBL5...)
Affinity DataIC50: 2.69E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115722(4-Cyclohexyl-[1,2]naphthoquinone | CHEMBL58737)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibitory activity against recombinant human Cdc25B using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115734(3-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-1H-indol...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115737(4-(1H-Indol-3-yl)-[1,2]naphthoquinone | CHEMBL6070...)
Affinity DataIC50: 3.07E+3nMAssay Description:In vitro inhibitory activity against recombinant human CD45 using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115722(4-Cyclohexyl-[1,2]naphthoquinone | CHEMBL58737)
Affinity DataIC50: 3.27E+3nMAssay Description:In vitro inhibitory activity against recombinant human CD45 using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115759(4-Hexyl-[1,2]naphthoquinone | CHEMBL57920)
Affinity DataIC50: 3.30E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115736(4-Cyclopentyl-[1,2]naphthoquinone | CHEMBL58288)
Affinity DataIC50: 4.20E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115745(3-(3,4-Dioxo-3,4-dihydro-naphthalen-1-yl)-1H-indol...)
Affinity DataIC50: 4.56E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115742(4-(2,5-Dichloro-phenyl)-[1,2]naphthoquinone | CHEM...)
Affinity DataIC50: 5.05E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115726(4-(4-Methoxy-phenyl)-[1,2]naphthoquinone | CHEMBL5...)
Affinity DataIC50: 5.24E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM36444(CHEMBL61245 | CID1550768 | ZINC01669713, 8)
Affinity DataIC50: 5.29E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115750(4-Biphenyl-4-yl-[1,2]naphthoquinone | CHEMBL58287)
Affinity DataIC50: 5.40E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50115752(4-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-[1,2]naphth...)
Affinity DataIC50: 5.73E+3nMAssay Description:In vitro inhibitory activity against recombinant human protein-tyrosine phosphatase 1B (PTP1B) using fluorescein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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