Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 1663
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13073(2000-07790 | 3-nitro-4-(2-oxopyrrolidin-1-yl)benze...)
Affinity DataIC50: 0.620nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13077(5-(thiophene-2-sulfonyl)thiophene-2-sulfonamide | ...)
Affinity DataIC50: 0.810nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13068(5-(thiophen-2-ylsulfanyl)thiophene-2-sulfonamide |...)
Affinity DataIC50: 0.890nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataIC50: 6.70nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13067(4-(3,5-dimethyl-1H-pyrazol-1-yl)benzene-1-sulfonam...)
Affinity DataIC50: 21.4nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13071(5-(pyridin-2-yl)thiophene-2-sulfonamide | 0191-86 ...)
Affinity DataIC50: 118nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13075(2000-01951 | 2,4-dichloro-5-sulfamoylbenzoic acid ...)
Affinity DataIC50: 170nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13069(ethyl 2-(4-sulfamoylphenoxy)propanoate | 0076-89 |...)
Affinity DataIC50: 186nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13072(0134-36 | 1-methyl-3-oxo-1,3-dihydro-2,1-benzothia...)
Affinity DataIC50: 246nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13070(0114-01 | 4-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol...)
Affinity DataIC50: 490nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13078(NRB01507 | 2-amino-2,3-dihydro-1,2,3-benzoxadiazol...)
Affinity DataIC50: 2.29E+3nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13076(JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...)
Affinity DataIC50: 5.50E+3nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13074(0164-08 | 2-[(4-chlorobenzene)sulfonyl]-N-hydroxya...)
Affinity DataIC50: 1.00E+6nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Marburg

LigandPNGBDBM13079(KM01987 | 2-(4,5-dichloro-2,5-dihydro-1H-imidazol-...)
Affinity DataIC50: 1.00E+6nMpH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/15/2007
Entry Details Article
PubMed