Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 1342
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10972((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 5nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10961(homotolserine | eseroline 2-ethylphenylcarbamate |...)
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10962((4aS,9aS)-2,4a,9-trimethyl-2H,3H,4H,4aH,9H,9aH-ind...)
Affinity DataIC50: 12nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM11023((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 16nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10972((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 22nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 22nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10958((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 24nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10968((4aS,9aS)-2,4a,9-trimethyl-2H,3H,4H,4aH,9H,9aH-ind...)
Affinity DataIC50: 25nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM11023((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 28nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 37nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10441((+)-Huperzine A | (13E)-1-amino-13-ethylidene-11-m...)
Affinity DataIC50: 47nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 47nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 50nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10970((4aS,9aS)-2,4a,9-trimethyl-2H,3H,4H,4aH,9H,9aH-ind...)
Affinity DataIC50: 65nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10963((1R,3aS,8aS)-1-hydroxy-1,3a,8-trimethyl-5-[(methyl...)
Affinity DataIC50: 100nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10971(CHF 2819 | (1R,3aS,8aS)-5-{[(2-ethylphenyl)carbamo...)
Affinity DataIC50: 125nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10964((4aS,9aS)-2,4a,9-trimethyl-2H,3H,4H,4aH,9H,9aH-ind...)
Affinity DataIC50: 130nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10962((4aS,9aS)-2,4a,9-trimethyl-2H,3H,4H,4aH,9H,9aH-ind...)
Affinity DataIC50: 150nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10966((4aS,9aS)-2,4a,9-trimethyl-2H,3H,4H,4aH,9H,9aH-ind...)
Affinity DataIC50: 175nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10967(2-methylphenylgeneserine.HCl | (1R,3aS,8aS)-1-hydr...)
Affinity DataIC50: 180nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 190nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10965((1R,3aS,8aS)-1-hydroxy-1,3a,8-trimethyl-5-[(phenyl...)
Affinity DataIC50: 200nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10970((4aS,9aS)-2,4a,9-trimethyl-2H,3H,4H,4aH,9H,9aH-ind...)
Affinity DataIC50: 310nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10963((1R,3aS,8aS)-1-hydroxy-1,3a,8-trimethyl-5-[(methyl...)
Affinity DataIC50: 660nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 760nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 800nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10964((4aS,9aS)-2,4a,9-trimethyl-2H,3H,4H,4aH,9H,9aH-ind...)
Affinity DataIC50: 815nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10958((3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyr...)
Affinity DataIC50: 1.56E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10966((4aS,9aS)-2,4a,9-trimethyl-2H,3H,4H,4aH,9H,9aH-ind...)
Affinity DataIC50: 1.57E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10971(CHF 2819 | (1R,3aS,8aS)-5-{[(2-ethylphenyl)carbamo...)
Affinity DataIC50: 1.70E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10959(tolserine.tartaric acid | 2-methylphenserine | (3a...)
Affinity DataIC50: 1.95E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10961(homotolserine | eseroline 2-ethylphenylcarbamate |...)
Affinity DataIC50: 2.90E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10620(3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-me...)
Affinity DataIC50: 4.15E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 4.15E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10969(4-isopropylphenylgeneserine.HCl | (1R,3aS,8aS)-1-h...)
Affinity DataIC50: 5.20E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 7.30E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10965((1R,3aS,8aS)-1-hydroxy-1,3a,8-trimethyl-5-[(phenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10967(2-methylphenylgeneserine.HCl | (1R,3aS,8aS)-1-hydr...)
Affinity DataIC50: 1.00E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10441((+)-Huperzine A | (13E)-1-amino-13-ethylidene-11-m...)
Affinity DataIC50: 1.00E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10968((4aS,9aS)-2,4a,9-trimethyl-2H,3H,4H,4aH,9H,9aH-ind...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10969(4-isopropylphenylgeneserine.HCl | (1R,3aS,8aS)-1-h...)
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed