Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50012380
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataIC50: 2.10nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118295(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataIC50: 2.70nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118289(7-Naphthalen-2-yl-8,9-dihydro-7H-7a,10-diaza-penta...)
Affinity DataIC50: 3.30nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)
Affinity DataIC50: 4.10nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(9-(4-Chloro-phenyl)-1,2,3,9-tetrahydro-4,9a-diaza-...)
Affinity DataIC50: 4.20nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118297(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataIC50: 8.40nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataIC50: 10.6nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Drew University

Curated by ChEMBL
LigandPNGBDBM50005536(Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...)
Affinity DataIC50: 12.9nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataIC50: 16.0nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)
Affinity DataIC50: 23.3nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118295(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataIC50: 34.2nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118292(10-(4-Chloro-phenyl)-2,10-dihydro-1H-3,10a-diaza-p...)
Affinity DataIC50: 36.1nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataIC50: 37.3nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118289(7-Naphthalen-2-yl-8,9-dihydro-7H-7a,10-diaza-penta...)
Affinity DataIC50: 38.1nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50005536(Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...)
Affinity DataIC50: 42.6nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118290(10-(4-Chloro-phenyl)-8,10-dihydro-9H-7,9a-diaza-pe...)
Affinity DataIC50: 218nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118296(5-Naphthalen-1-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)
Affinity DataIC50: 1.84E+3nMAssay Description:Ability to displace [3H]WIN-35428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(9-(4-Chloro-phenyl)-1,2,3,9-tetrahydro-4,9a-diaza-...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataKi:  2.01nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118289(7-Naphthalen-2-yl-8,9-dihydro-7H-7a,10-diaza-penta...)
Affinity DataKi:  2.83nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118289(7-Naphthalen-2-yl-8,9-dihydro-7H-7a,10-diaza-penta...)
Affinity DataKi:  5.20nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrine transporter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataKi:  5.30nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrine transporter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118294(7-(4-Chloro-phenyl)-7,8,9,10-tetrahydro-7a,11-diaz...)
Affinity DataKi:  5.5nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)
Affinity DataKi:  11nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrine transporter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118289(7-Naphthalen-2-yl-8,9-dihydro-7H-7a,10-diaza-penta...)
Affinity DataKi:  11nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50005536(Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...)
Affinity DataKi:  18nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrine transporter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(9-(4-Chloro-phenyl)-1,2,3,9-tetrahydro-4,9a-diaza-...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]RTI-55 from human Norepinephrine transporter expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataKi:  27.2nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataKi:  33.4nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrine transporter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50055003(9-(4-Chloro-phenyl)-1,2,3,9-tetrahydro-4,9a-diaza-...)
Affinity DataKi:  39nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50005536(Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...)
Affinity DataKi:  45nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)
Affinity DataKi:  45nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50005536(Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...)
Affinity DataKi:  50nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118295(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataKi:  152nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118293(7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...)
Affinity DataKi:  224nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118295(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataKi:  600nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Drew University

Curated by ChEMBL
LigandPNGBDBM50118295(11-(4-Chloro-phenyl)-5a,7,8,9,9a,11-hexahydro-6H-b...)
Affinity DataKi:  690nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrine transporter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed