Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50012389
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  4.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  4.40E+3nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  1.00E+4nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM26431((2R)-2-aminopentanedioic acid | D-Glu | D-Glutamat...)
Affinity DataEC50:  1.20E+4nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50:  3.50E+4nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118479(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50:  3.70E+4nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118480(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50:  4.00E+4nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118480(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50:  1.90E+5nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089901(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataEC50:  2.50E+5nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein lifeguard 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118479(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataIC50: 2.87E+5nMAssay Description:Binding affinity towards N-methyl-D-aspartate glutamate receptor (NMDA) determined electrophysically using the rat cortical wedge model.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089901(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataEC50:  4.90E+5nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060718((R)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-b...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118479(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118480(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060718((R)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-b...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060718((R)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-b...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060719(2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060719(2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118479(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060719(2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089901(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060718((R)-2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-b...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118480(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118481(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118481(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118481(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50089901(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118479(2-Amino-4-(4-hydroxy-[1,2,5]thiadiazol-3-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50118481(2-Amino-3-(3-hydroxy-isoxazol-5-yl)-propionic acid...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50060719(2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyr...)
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Rat)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50052553((2S)-2-aminohexanedioic acid | L-2-aminoadipic aci...)
Affinity DataEC50: >3.00E+6nMAssay Description:Compound was evaluated for the inhibitory activity against cloned Metabotropic glutamate receptor 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed