Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50012401
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118598(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  0.450nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  0.710nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118600(2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperid...)
Affinity DataKi:  0.730nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118601(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-f...)
Affinity DataKi:  0.990nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118606(1-Benzofuran-2-ylmethyl-4-{2-[bis-(4-fluoro-phenyl...)
Affinity DataKi:  1.01nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50049363(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118605(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-t...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118604(1-(benzo[b]thiophen-2-ylmethyl)-4-(2-(bis(4-fluoro...)
Affinity DataKi:  1.61nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 4.30nMAssay Description:The inhibition of reuptake against dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118603(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataIC50: 7.20nMAssay Description:Compound was tested for the inhibition of dopamine (DA) reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118604(1-(benzo[b]thiophen-2-ylmethyl)-4-(2-(bis(4-fluoro...)
Affinity DataIC50: 11.9nMAssay Description:Compound was tested for the inhibition of dopamine (DA) reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50118602(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-naph...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards dopamine transporter (DAT) by using [125I]RTI-55 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118601(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-f...)
Affinity DataKi:  41nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118605(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-t...)
Affinity DataKi:  45nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118598(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  47nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50049363(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  68nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 73nMAssay Description:The inhibition of reuptake against Serotonin transporter (5-HT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataIC50: 79nMAssay Description:Compound was tested for the inhibition of norepinephrine (NE) reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118606(1-Benzofuran-2-ylmethyl-4-{2-[bis-(4-fluoro-phenyl...)
Affinity DataKi:  85nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118600(2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperid...)
Affinity DataKi:  88nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataIC50: 93nMAssay Description:Compound was tested for the inhibition of norepinephrine (NE) reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM22165(Vanoxerine | CHEMBL542933 | GBR-12909 | CHEMBL5438...)
Affinity DataKi:  126nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118603(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(3-p...)
Affinity DataKi:  164nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataKi:  229nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118604(1-(benzo[b]thiophen-2-ylmethyl)-4-(2-(bis(4-fluoro...)
Affinity DataKi:  246nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118604(1-(benzo[b]thiophen-2-ylmethyl)-4-(2-(bis(4-fluoro...)
Affinity DataIC50: 260nMAssay Description:Compound was tested for the inhibition of norepinephrine (NE) reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118599(4-(2-(bis(4-fluorophenyl)methoxy)ethyl)-1-(naphtha...)
Affinity DataIC50: 277nMAssay Description:Compound was tested for the inhibition of serotonin (5-HT) reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118602(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-naph...)
Affinity DataKi:  370nMAssay Description:Binding affinity for serotonin transporter (SERT) using [125I]RTI-55More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50118604(1-(benzo[b]thiophen-2-ylmethyl)-4-(2-(bis(4-fluoro...)
Affinity DataIC50: 1.04E+3nMAssay Description:Compound was tested for the inhibition of serotonin (5-HT) reuptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed