Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50037075
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.130nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity against progesterone receptor (PR) using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118693(6-(3-Chloro-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118698(6-(3-Fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity against the Androgen Receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118698(6-(3-Fluoro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50: 8.20nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118700(6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118695(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 9.90nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118696(5-(4,4-dimethyl-2-oxo-2,4-dihydro-1H-benzo[d][1,3]...)
Affinity DataIC50: 15.1nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 15.9nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 15.9nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118695(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 17nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118697(6-(3-Methoxy-phenyl)-4,4-dimethyl-1,4-dihydro-benz...)
Affinity DataIC50: 19.5nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118689(3-Fluoro-5-(8-fluoro-4,4-dimethyl-2-oxo-1,4-dihydr...)
Affinity DataIC50: 26.2nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118692(6-(4-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118700(6-(3-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50: 30nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50: 37nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50: 37nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118697(6-(3-Methoxy-phenyl)-4,4-dimethyl-1,4-dihydro-benz...)
Affinity DataIC50: 38.3nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 40.2nMAssay Description:Antagonist activity against the Progesterone Receptor (PR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 40.2nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118696(5-(4,4-dimethyl-2-oxo-2,4-dihydro-1H-benzo[d][1,3]...)
Affinity DataIC50: 55nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50:  61.1nMAssay Description:Agonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataEC50:  90nMAssay Description:Agonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118689(3-Fluoro-5-(8-fluoro-4,4-dimethyl-2-oxo-1,4-dihydr...)
Affinity DataIC50: 98.8nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 129nMAssay Description:Antagonist activity against the Androgen Receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50: 207nMAssay Description:Antagonist activity against the Androgen Receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 280nMAssay Description:Antagonist activity against the Androgen Receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118699(6-(2-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118699(6-(2-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50: 500nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118693(6-(3-Chloro-5-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataEC50:  500nMAssay Description:Agonist activity against progesterone receptor (PR) in an alkaline phosphatase assay in the T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118692(6-(4-Chloro-phenyl)-4,4-dimethyl-1,4-dihydro-benzo...)
Affinity DataIC50: 642nMAssay Description:Antagonist activity against progesterone receptor (PR) in an assay using PRE-luciferase plasmid co-transfected CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM18627(Mifeprex | (10S,11S,14S,15S,17R)-17-[4-(dimethylam...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity against the Mineralocorticoid Receptor (MR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 1.29E+3nMAssay Description:Antagonist activity against the Androgen Receptor (AR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 1.39E+3nMAssay Description:Antagonist activity against the Mineralocorticoid Receptor (MR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 1.76E+3nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118688(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 1.86E+3nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118690(3-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 2.37E+3nMAssay Description:Antagonist activity against the Mineralocorticoid Receptor (MR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50: 2.49E+3nMAssay Description:Antagonist activity against the Mineralocorticoid Receptor (MR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118691(6-(3-Chloro-4-fluoro-phenyl)-4,4-dimethyl-1,4-dihy...)
Affinity DataIC50: 2.58E+3nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against the Glucocorticoid Receptor (GR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Women'S Health Research Institute

Curated by ChEMBL
LigandPNGBDBM50118694(4-(4,4-Dimethyl-2-oxo-1,4-dihydro-2H-benzo[d][1,3]...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity against the Mineralocorticoid Receptor (MR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed