Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50012441
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118906(3-{2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hydro...)
Affinity DataIC50: 15nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118904({2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hydroxy...)
Affinity DataIC50: 15nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118907(1-{2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hydro...)
Affinity DataIC50: 18nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50409606(CHEMBL2111970)
Affinity DataIC50: 18nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118902(({2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hydrox...)
Affinity DataIC50: 18nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50409607(CHEMBL2112799)
Affinity DataIC50: 21nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118905(2-{2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hydro...)
Affinity DataIC50: 28nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118901(4-{2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hydro...)
Affinity DataIC50: 32nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118894(5-{2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hydro...)
Affinity DataIC50: 38nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118898((1-{2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hydr...)
Affinity DataIC50: 45nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118896(3-(1-{2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hy...)
Affinity DataIC50: 61nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118893(4-(1-{2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hy...)
Affinity DataIC50: 70nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118897((1-{2-[1-(3-Acetoxy-2,2-dimethyl-propyl)-7-chloro-...)
Affinity DataIC50: 78nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118903(Propionic acid 3-[3-[2-(4-carboxymethyl-piperidin-...)
Affinity DataIC50: 87nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118892(Isobutyric acid 3-[3-[2-(4-carboxymethyl-piperidin...)
Affinity DataIC50: 89nMAssay Description:Inhibitory activity against squalene synthase derived from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118900(Butyric acid 3-[3-[2-(4-carboxymethyl-piperidin-1-...)
Affinity DataIC50: 93nMAssay Description:Inhibition of squalene synthase from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50118899((1-{2-[1-(3-tert-Butoxycarbonylmethoxy-2,2-dimethy...)
Affinity DataIC50: 471nMAssay Description:Inhibitory activity against squalene synthase derived from human hepatoma cells (HepG2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed