Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50035258
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataIC50: 74nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119074(N-[4-(3-Chloro-4-fluoro-phenylamino)-3-cyano-7-(3-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataIC50: 83nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 515nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM4779(cid_156414 | PD0183805 | CHEMBL545315 | CHEMBL3196...)
Affinity DataIC50: 529nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119073(4-(3-Ethynyl-phenylamino)-6,7-bis-(2-methoxy-ethox...)
Affinity DataIC50: 850nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119071(4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-6-(3-m...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-etho...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of Epidermal Growth Factor Receptor (EGFR) autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119074(N-[4-(3-Chloro-4-fluoro-phenylamino)-3-cyano-7-(3-...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119073(4-(3-Ethynyl-phenylamino)-6,7-bis-(2-methoxy-ethox...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50119071(4-(3-Chloro-4-fluoro-phenylamino)-7-methoxy-6-(3-m...)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human epidermal growth factor receptor-2 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2012
Entry Details Article
PubMed