Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50012605
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120987([(S)-1-((4S,6R,6aS)-6-Ethyl-4-methanesulfonyl-5-ox...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120985([(S)-1-((6R,6aS)-6-Ethyl-4-methanesulfonyl-5-oxo-h...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120984([(S)-1-((4S,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120987([(S)-1-((4S,6R,6aS)-6-Ethyl-4-methanesulfonyl-5-ox...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986([(S)-1-((4R,6R,6aS)-6-Ethyl-4-methanesulfonyl-5-ox...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120985([(S)-1-((6R,6aS)-6-Ethyl-4-methanesulfonyl-5-oxo-h...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 2 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986([(S)-1-((4R,6R,6aS)-6-Ethyl-4-methanesulfonyl-5-ox...)
Affinity DataIC50: 8.80E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120984([(S)-1-((4S,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 9.90E+4nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120985([(S)-1-((6R,6aS)-6-Ethyl-4-methanesulfonyl-5-oxo-h...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983([(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 1.47E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 hr preincubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120984([(S)-1-((4S,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 1.72E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120985([(S)-1-((6R,6aS)-6-Ethyl-4-methanesulfonyl-5-oxo-h...)
Affinity DataIC50: 1.82E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986([(S)-1-((4R,6R,6aS)-6-Ethyl-4-methanesulfonyl-5-ox...)
Affinity DataIC50: 1.93E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120986([(S)-1-((4R,6R,6aS)-6-Ethyl-4-methanesulfonyl-5-ox...)
Affinity DataIC50: 1.94E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983([(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 2.16E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50: 2.84E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120984([(S)-1-((4S,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 3.41E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983([(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120982((S)-4-Acetylamino-4-[2-carboxy-1-((S)-1-{(S)-1-[(S...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 4 hr pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50120983([(S)-1-((4R,6R,6aS)-4-Acetyl-6-ethyl-5-oxo-hexahyd...)
Affinity DataIC50: 4.47E+5nMAssay Description:Inhibitory concentration against hepatitis C virus NS3/4A protease on 18 h pre-incubation in fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed