Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50023927
TargetDNA topoisomerase 2-alpha(Human)
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50250882((23R,25R)-3,4-seco-9beta-H-lanosta-4(28),7-dien-26...)
Affinity DataIC50: 4.26E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50250883((2R,4S,6R)-6-((3R,3aR,5aS,6S,7S,9bR)-6-(3-hydroxyp...)
Affinity DataIC50: 5.04E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50250884((2R,6R)-methyl 6-((3R,3aR,5aS,6S,7S,9bR)-6-(3-meth...)
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 7.57E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDNA topoisomerase 2-alpha(Human)
Osaka University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50250881(Methyl (23R,25R)-3,4-seco-9beta-H-lanosta-4(28),7-...)
Affinity DataIC50: 7.57E+4nMAssay Description:Inhibition of human DNA topoisomerase 2alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed