Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50012844
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123247((S)-3-{[5-(3-Guanidino-phenyl)-thiophene-2-carbony...)
Affinity DataIC50: 0.000920nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123246((S)-2-Benzenesulfonylamino-3-{[5-(4-guanidino-phen...)
Affinity DataIC50: 0.00130nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123251((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidinomethy...)
Affinity DataIC50: 0.00580nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123251((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidinomethy...)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123253((S)-3-{[5-(3-Guanidinomethyl-phenyl)-thiophene-2-c...)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123249((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phen...)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123252((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidino-phen...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123247((S)-3-{[5-(3-Guanidino-phenyl)-thiophene-2-carbony...)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123248((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidinomethy...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123249((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phen...)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123248((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidinomethy...)
Affinity DataIC50: 0.740nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123249((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phen...)
Affinity DataIC50: 1nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123247((S)-3-{[5-(3-Guanidino-phenyl)-thiophene-2-carbony...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123250((S)-2-Benzenesulfonylamino-3-{[5-(4-guanidinomethy...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123251((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidinomethy...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of vitronectin binding to HT-29 cells expressing integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123248((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidinomethy...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123247((S)-3-{[5-(3-Guanidino-phenyl)-thiophene-2-carbony...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of vitronectin binding to HT-29 cells expressing integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123253((S)-3-{[5-(3-Guanidinomethyl-phenyl)-thiophene-2-c...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123250((S)-2-Benzenesulfonylamino-3-{[5-(4-guanidinomethy...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123249((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phen...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of vitronectin binding to HT-29 cells expressing integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123253((S)-3-{[5-(3-Guanidinomethyl-phenyl)-thiophene-2-c...)
Affinity DataIC50: 11nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123253((S)-3-{[5-(3-Guanidinomethyl-phenyl)-thiophene-2-c...)
Affinity DataIC50: 11nMAssay Description:Inhibition of vitronectin binding to HT-29 cells expressing integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123251((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidinomethy...)
Affinity DataIC50: 21nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123247((S)-3-{[5-(3-Guanidino-phenyl)-thiophene-2-carbony...)
Affinity DataIC50: 26nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alpha5-beta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123253((S)-3-{[5-(3-Guanidinomethyl-phenyl)-thiophene-2-c...)
Affinity DataIC50: 71nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alpha5-beta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123248((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidinomethy...)
Affinity DataIC50: 72nMAssay Description:Inhibition of vitronectin binding to HT-29 cells expressing integrin alphaV-beta5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123246((S)-2-Benzenesulfonylamino-3-{[5-(4-guanidino-phen...)
Affinity DataIC50: 72nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123249((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidino-phen...)
Affinity DataIC50: 95nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alpha5-beta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123248((S)-2-Benzenesulfonylamino-3-{[5-(3-guanidinomethy...)
Affinity DataIC50: 640nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alpha5-beta1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123250((S)-2-Benzenesulfonylamino-3-{[5-(4-guanidinomethy...)
Affinity DataIC50: 730nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123246((S)-2-Benzenesulfonylamino-3-{[5-(4-guanidino-phen...)
Affinity DataIC50: 3.79E+3nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123252((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidino-phen...)
Affinity DataIC50: 5.33E+3nMAssay Description:Inhibition of fibrinogen binding to K562 cells expressing integrin alphaV-beta3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50123252((S)-2-Benzenesulfonylamino-3-{[5-(2-guanidino-phen...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of fibrinogen binding to integrin alphaV-beta3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed