Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50012861
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123468([3-Benzyl-5-(1,1-dioxo-1lambda 6 -isothiazolidin-2...)
Affinity DataEC50: >800nMAssay Description:Potency of compound was tested against HIV-1- containing integrase mutations (T66I, S153Y)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123468([3-Benzyl-5-(1,1-dioxo-1lambda 6 -isothiazolidin-2...)
Affinity DataEC50:  140nMAssay Description:Potency of compound was tested against HIV-1- containing integrase mutations (NL4-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123468([3-Benzyl-5-(1,1-dioxo-1lambda 6 -isothiazolidin-2...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23400((2Z)-4-(3-benzylphenyl)-2-hydroxy-4-oxobut-2-enoic...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123469((3-benzylphenyl)(8-hydroxy-1,6-naphthyridin-7-yl)m...)
Affinity DataIC50: 40nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123471((4-benzylpyridin-2-yl)(8-hydroxyquinolin-7-yl)meth...)
Affinity DataIC50: 50nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123470(CHEMBL35842 | 7-(3-benzylbenzoyl)quinolin-8-ol (Co...)
Affinity DataIC50: 370nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123472(7-Benzyl-1,2-dihydroxy-xanthen-9-one | CHEMBL28809...)
Affinity DataIC50: 600nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50123467((3-Benzyl-phenyl)-(3-hydroxy-furo[3,2-b]pyridin-2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for its ability to inhibit the strand transfer of the integration process catalyzed by HIV integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed