Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50013038
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataEC50:  2.24nMAssay Description:Agonist potency determined by [35S]GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataEC50:  0.100nMAssay Description:Agonist potency determined by [35S]GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataEC50:  1.56nMAssay Description:Agonist potency determined by [35S]GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataEC50:  0.490nMAssay Description:Agonist potency determined by [35S]GTP gamma-S binding assay using CHO cell lines for Melatonin receptor type 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125758(N-[2-(7-{10-[8-(2-Acetylamino-ethyl)-naphthalen-2-...)
Affinity DataKi:  0.0300nMAssay Description:Binding affinity for human Melatonin receptor type 1A stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125758(N-[2-(7-{10-[8-(2-Acetylamino-ethyl)-naphthalen-2-...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity for human Melatonin receptor type 1B stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125755(N-[2-(7-{5-[8-(2-Acetylamino-ethyl)-naphthalen-2-y...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity for human Melatonin receptor type 1A stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125752(N-[2-(7-{8-[8-(2-Acetylamino-ethyl)-naphthalen-2-y...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity for human Melatonin receptor type 1A stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity for human Melatonin receptor type 1A stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125753(N-[2-(7-{6-[8-(2-Acetylamino-ethyl)-naphthalen-2-y...)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity for human Melatonin receptor type 1A stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity for human Melatonin receptor type 1A stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125752(N-[2-(7-{8-[8-(2-Acetylamino-ethyl)-naphthalen-2-y...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity for human Melatonin receptor type 1B stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50035179(S 20098 | N-[2-(7-Methoxy-naphthalen-1-yl)-ethyl]-...)
Affinity DataKi:  0.270nMAssay Description:Binding affinity for human Melatonin receptor type 1B stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity for human Melatonin receptor type 1B stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125754(N,N'-(2,2'-(7,7'-(propane-1,3-diylbis(oxy))bis(nap...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity for human Melatonin receptor type 1A stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125757(N,N'-(2,2'-(7,7'-(butane-1,4-diylbis(oxy))bis(naph...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity for human Melatonin receptor type 1A stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125755(N-[2-(7-{5-[8-(2-Acetylamino-ethyl)-naphthalen-2-y...)
Affinity DataKi:  1.74nMAssay Description:Binding affinity for human Melatonin receptor type 1B stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125756(N-[2-(7-{2-[8-(2-Acetylamino-ethyl)-naphthalen-2-y...)
Affinity DataKi:  2.05nMAssay Description:Binding affinity for human Melatonin receptor type 1A stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125753(N-[2-(7-{6-[8-(2-Acetylamino-ethyl)-naphthalen-2-y...)
Affinity DataKi:  2.33nMAssay Description:Binding affinity for human Melatonin receptor type 1B stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125757(N,N'-(2,2'-(7,7'-(butane-1,4-diylbis(oxy))bis(naph...)
Affinity DataKi:  72.7nMAssay Description:Binding affinity for human Melatonin receptor type 1B stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125754(N,N'-(2,2'-(7,7'-(propane-1,3-diylbis(oxy))bis(nap...)
Affinity DataKi:  112nMAssay Description:Binding affinity for human Melatonin receptor type 1B stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50125756(N-[2-(7-{2-[8-(2-Acetylamino-ethyl)-naphthalen-2-y...)
Affinity DataKi:  182nMAssay Description:Binding affinity for human Melatonin receptor type 1B stably transfected in human embryonic kidney cells (HEK 293) using 2-[125I]iodomelatonin as rad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed