Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 1212
LigandPNGBDBM10083((Z)-4-(3-Hydroxy-piperidinyl)-3-(3-methoxy-1H-pyrr...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10085((Z)-4-(3-Hydroxymethyl-piperidinyl)-3-(3-methoxy-1...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10091((-)-(R)-(Z)-4-(3-Amino-pyrrolidinyl)-3-(3-methoxy-...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10092(N-[(3R)-1-[(3Z)-3-[(3-methoxy-1H-pyrrol-2-yl)methy...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10081((-)-(R)-(Z)-4-(3-Hydroxy-pyrrolidinyl)-3-(3-methox...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10084((Z)-4-(4-Hydroxy-piperidinyl)-3-(3-methoxy-1H-pyrr...)
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10089((3Z)-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-5-n...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10090((3Z)-4-(4-aminopiperidin-1-yl)-3-[(3-methoxy-1H-py...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10080((3S)-1-[(3Z)-3-[(3-methoxy-1H-pyrrol-2-yl)methylid...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10082((+)-(S)-(Z)-4-(3-Hydroxy-pyrrolidinyl)-3-(3-methox...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10087((Z)-4-(3-Hydroxy-cyclopentylamino)-3-(3-methoxy-1H...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10088((Z)-4-(3-Amino-cyclopentylamino)-3-(3-methoxy-1H-p...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10079((Z)-1-[3-(3-Methoxy-1H-pyrrol-2-ylmethylene)-5-nit...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10086((Z)-4-(4-Hydroxy-cyclohexylamino)-3-(3-methoxy-1H-...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10078((Z)-4-[3-(3-Methoxy-1H-pyrrol-2-ylmethylene)-5-nit...)
Affinity DataIC50: 28nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10076((3Z)-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-5-n...)
Affinity DataIC50: 39nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10075((3Z)-5-methoxy-3-[(3-methoxy-1H-pyrrol-2-yl)methyl...)
Affinity DataIC50: 209nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10074((3Z)-5-fluoro-3-[(3-methoxy-1H-pyrrol-2-yl)methyli...)
Affinity DataIC50: 847nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10077((3Z)-4-(1H-imidazol-1-yl)-3-[(3-methoxy-1H-pyrrol-...)
Affinity DataIC50: 1.75E+3nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed
LigandPNGBDBM10073((3Z)-3-[(3-methoxy-1H-pyrrol-2-yl)methylidene]-2,3...)
Affinity DataIC50: 5.36E+3nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using a recombinant human cyclin E-CDK2 complex. The enzyme was assayed with substrate in the presence of 1uM ATP/[gamma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2006
Entry Details Article
PubMed